...Jean-Luc Darlix; Hugues de Rocquigny; Yves Mély Retroviruses are enveloped plus-strand RNA viruses that can cause cancer, immunodeficiency and neurological disorder in human and animals. Retroviruses have several unique properties, such as a genomic RNA in a dimeric form found in the virus...

.... These findings run counter to the widespread presumption that the endosome is a major site of vesicle biogenesis. However, they are highly similar to what has been found for retrovirus budding, a process that is driven by Gag, the major structural protein of retroviruses. Specifically, it has been demonstrated...

... division and are co-opted by enveloped retroviruses to facilitate viral egress. Analysis of these functions may help illuminate conserved mechanisms of ESCRT function. 1 To whom correspondence should be addressed (email Juan.Martin-Serrano@kcl.ac.uk ). 25 9 2008 © The Authors Journal...