... was enabled by the participation of University of Kentucky in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society. E3 ligase photoreceptor retina Siah ubiquitin The ubiquitin proteasomal system (UPS) is a highly selective post-translational mechanism...

... trafficking defects and morphology. Correspondence: Toby W. Hurd ( toby.hurd@igmm.ed.ac.uk ) 4 7 2018 26 9 2018 12 10 2018 The tri-laminar retina has evolved to process light waves from our environment and deliver them to the occipital lobe for visual processing...

... Biochemical Society 2014 angiogenesis decoy myeloid Notch tumour retina Angiogenesis is a well-orchestrated sequence of events involving endothelial proliferation, migration, sprouting, lumen formation and vessel maturation. New sprouts generated by angiogenesis eventually form patent...

...David S. Williams; Vanda S. Lopes Mutations in MYO7A (myosin VIIa) cause Usher syndrome type 1B, a disorder involving profound congenital deafness and progressive blindness. In the retina, most MYO7A is localized in the apical region of the RPE (retinal pigmented epithelial) cells, and a small...

... development is little characterized. The retina provides an excellent model system to study autophagy in the context of neural development, and to establish its relationship with proliferation, differentiation and cell death. In the present review, we summarize recent findings showing that autophagy...