... with a copper chelator that inhibits SOD1 and leads to peroxynitrite-dependent cell death. The latter approach effectively kills lymphoma cells that overexpress the anti-apoptotic protein Bcl-2. Given the central role of mitochondria in redox homoeostasis, metabolism and the intrinsic pathway to apoptosis, our...

... mitochondrial intermembrane space (IMS) proteome redox homoeostasis Eukaryotic cells contain different compartments with defined proteomes which allows for the spatiotemporal separation of various catalytic processes. However, not all processes differ between different compartments and many pathways...

.... In the present paper, I discuss the consequences of these new findings for our understanding of glutathione homoeostasis in the eukaryotic cell. glutathione glutathione transport redox homoeostasis reduction-oxidation-sensitive GFP 2 (roGFP2) yeast cadmium factor 1 (Ycf1) Redox signalling...

... be addressed (email areddy@cantab.net ). 14 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 circadian rhythm peroxiredoxin reactive oxygen species (ROS) redox homoeostasis Circadian rhythms are arguably one of life's most basic mechanisms, regulating...

... ). 13 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 carbon metabolism mitochondrial electron transport NAD(P)H redox homoeostasis stress The pyridine nucleotides NAD(H) and NADP(H) are central mediators of reductant energy between metabolic processes...