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Keywords: reactive oxygen species (ROS)
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Articles
Biochem Soc Trans (2016) 44 (4): 1111–1116.
Published: 15 August 2016
...) and isocitrate dehydrogenase (IDH) focusing on the similarity between the phenotypes of cancers harbouring these mutations. cancer metabolism fumarate hydratase hypoxia isocitrate dehydrogenase reactive oxygen species (ROS) succinate dehydrogenase Dysfunction in IDH, SDH and FH are also involved...
Articles
Biochem Soc Trans (2015) 43 (4): 680–686.
Published: 03 August 2015
... such as reactive oxygen species (ROS) and electrophilic xenobiotics, effectively providing a cellular survival mechanism. This cytoprotective activity of Nrf2 has been implicated in disease prevention, including cancer [ 5 – 8 ]. In the case of cancer, controlled Nrf2 up-regulation has shown to protect against...
Articles
Biochem Soc Trans (2014) 42 (4): 922–927.
Published: 11 August 2014
... family members, is central to these processes. ageing oxidation reactive oxygen species (ROS) rheumatoid arthritis thiol thioredoxin There is a requirement for oxidoreductase activity for the processing and presentation of disulfide-cross-linked antigens by macrophages and dendritic cells...
Articles
Biochem Soc Trans (2014) 42 (4): 934–938.
Published: 11 August 2014
... peroxide (H 2 O 2 ) NADPH oxidase (Nox) reactive oxygen species (ROS) signalling Redox Regulation in Health and Disease: a Celebration of 50 Years of the Keilin Memorial Lecture: A Biochemical Society Focused Meeting held at The Royal Society, Edinburgh, U.K., 19–21 March 2014. Organized...
Articles
Biochem Soc Trans (2014) 42 (4): 959–964.
Published: 11 August 2014
... antioxidant autism spectrum disorder mitochondrial disease oxidative stress reactive oxygen species (ROS) redox imaging RTT (Rett syndrome) was initially described in 1966 as an “unusual brain atrophy syndrome” [ 1 , 2 ]. It primarily affects girls with a prevalence of 1:10000–15000...
Articles
Biochem Soc Trans (2014) 42 (2): 370–376.
Published: 20 March 2014
... (email V.E.Franklin-Tong@bham.ac.uk ). 25 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cytoskeleton nitric oxide (NO) Papaver pollen programmed cell death (PCD) reactive oxygen species (ROS) self-incompatibility Successful sexual...
Articles
Biochem Soc Trans (2014) 42 (1): 1–10.
Published: 23 January 2014
... be addressed (email areddy@cantab.net ). 14 10 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 circadian rhythm peroxiredoxin reactive oxygen species (ROS) redox homoeostasis Circadian rhythms are arguably one of life's most basic mechanisms, regulating...
Articles
Biochem Soc Trans (2012) 40 (4): 735–738.
Published: 20 July 2012
... levels produced during prion infection, but the C2 produced may provide a PrP Sc seed that maintains the prion conversion process. chronic demyelinating polyneuropathy cleavage Creutzfeldt–Jakob disease octapeptide repeat prion processing reactive oxygen species (ROS) As for numerous...
Articles
Biochem Soc Trans (2012) 40 (1): 129–132.
Published: 19 January 2012
... in FTHS, the fact that several other podosome-associated proteins are mutated in disorders involving craniofacial and other skeletal abnormalities suggests that this is an idea worth pursuing in the future [ 13 ]. atherosclerosis cancer embryonic development reactive oxygen species (ROS...
Articles
Biochem Soc Trans (2011) 39 (6): 1683–1686.
Published: 21 November 2011
... muscular dystrophy (EDMD) Hutchinson–Gilford progeria syndrome (HGPS) induced pluripotent stem cell (iPSC) nuclear envelope disease reactive oxygen species (ROS) The Nuclear Envelope Disease and Chromatin Organization UK was formed in 2005, to unite and promote collaborations between...
Articles
Biochem Soc Trans (2011) 39 (6): 1715–1718.
Published: 21 November 2011
... Society 2011 DNA damage response Hutchinson–Gilford progeria syndrome (HGPS) lamin laminopathy progeria reactive oxygen species (ROS) The progeroid laminopathies include HGPS (Hutchinson–Gilford progeria syndrome), atypical Werner's syndrome, MAD (mandibuloacral dysplasia) and RD...
Articles
Biochem Soc Trans (2011) 39 (5): 1221–1225.
Published: 21 September 2011
... dichlorodihydrofluorescein or dihydrorhodamine. 1 email balarama@mcw.edu . 15 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cell signalling fluorescence mitochondrion reactive nitrogen species (RNS) reactive oxygen species (ROS) redox biology superoxide...
Articles
Biochem Soc Trans (2011) 39 (5): 1305–1309.
Published: 21 September 2011
... correspondence should be addressed (email irina.shabalina@wgi.su.se ). 15 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 carbonyl cyanide p -trifluoromethoxyphenylhydrazone (FCCP) membrane potential mitochondrion oxidative stress reactive oxygen species (ROS...
Articles
Biochem Soc Trans (2011) 39 (5): 1471–1475.
Published: 21 September 2011
... signalling quorum sensing reactive oxygen species (ROS) stress defence and dying yeast colony architecture and differentiation Most knowledge of yeast cell reproduction, aging and dying comes from laboratory investigations, where cells are often treated in liquid cultures grown under various...
Articles
Biochem Soc Trans (2011) 39 (5): 1226–1232.
Published: 21 September 2011
... 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 advanced glycation end-product (AGE) reactive nitrogen species (RNS) reactive oxygen species (ROS) reactive sulfur species (RSS) rheumatoid arthritis (RA) RA (rheumatoid arthritis) is an inflammatory...
Articles
Biochem Soc Trans (2011) 39 (5): 1273–1278.
Published: 21 September 2011
... inflammation reactive oxygen species (ROS) redox signalling regulatory T-cell (T reg cell) The principal function of the immune system is to discriminate between self and non-self, and the effector T-cell arm (including TH1, TH2 and TH17; see Figure 1 ) is responsible, along with the B-cell arm...
Articles
Biochem Soc Trans (2011) 39 (5): 1538–1543.
Published: 21 September 2011
... Society 2011 cytochrome c mitochondrion programmed cell death (PCD) reactive oxygen species (ROS) Saccharomyces cerevisiae YCA1 The term PCD (programmed cell death) describes a highly heterogeneous process regulated by distinct but sometimes overlapping pathways including apoptosis...
Articles
Biochem Soc Trans (2011) 39 (5): 1544–1548.
Published: 21 September 2011
... should be addressed (email ggoldman@usp.br ). 24 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 Aspergillus nidulans cell death endoplasmic reticulum farnesol reactive oxygen species (ROS) FOH (farnesol), a non-sterol isoprenoid produced...
Articles
Biochem Soc Trans (2011) 39 (5): 1288–1292.
Published: 21 September 2011
... 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 electrochemical detection isolated mitochondrion macrophage optical nanosensor reactive oxygen species (ROS) superoxide dismutase (SOD) ROS (reactive oxygen species) such as superoxide (O 2 – ) play...
Articles
Biochem Soc Trans (2008) 36 (5): 976–980.
Published: 19 September 2008
... mitochondrion NADH:ubiquinone oxidoreductase oxidative stress reactive oxygen species (ROS) reverse electron transport Information about the site(s) of ROS production of complex I is provided by differences in the rates of ROS production (observed in mitochondria and submitochondrial particles...
Articles
Biochem Soc Trans (2008) 36 (5): 930–934.
Published: 19 September 2008
...-1 β-cells [ 51 ]. diabetes lipotoxicity mitochondrial DNA (mtDNA) oxidative stress pancreatic β-cell reactive oxygen species (ROS) Pancreatic β-cells are poised to sense glucose and other nutrient secretagogues to regulate insulin exocytosis, thereby maintaining glucose...
Articles
Biochem Soc Trans (2007) 35 (1): 28–32.
Published: 22 January 2007
... metabolism protein phosphorylation photosynthesis reactive oxygen species (ROS) sucrose phosphate synthase (SPS) This review focuses on phosphorylation and signalling in plants. It takes quite a broad overview of the subject, but, within that, highlights topics that are current research interests...
Articles
Biochem Soc Trans (2005) 33 (6): 1394–1396.
Published: 26 October 2005
... oxygen species (ROS) superoxide production In neurons, NO inhibition of mitochondrial respiration results in glutamate release, which kills by excitotoxic mechanisms and this cell death is greater in hypoxic conditions [ 7 – 9 ]. Activated, iNOS-expressing glia or low concentrations of NO from...
Articles
Biochem Soc Trans (2005) 33 (6): 1385–1389.
Published: 26 October 2005
...) lysophosphatidylcholine mitochondrion oxidized lipid reactive oxygen species (ROS) thiol The formation of low molecular mass second messengers as cell-signalling molecules is well established in the redox cell-signalling field. The molecules involved in signalling are structurally diverse and include the ROS...
Articles
Biochem Soc Trans (2005) 33 (5): 1123–1125.
Published: 26 October 2005
... stress. neurodegeneration octapeptide repeat oxidative stress prion protein (PrP) proteolysis reactive oxygen species (ROS) Prion diseases occur when a conformational conversion in the normal PrP C [cellular isoform of PrP (prion protein)] produces a proteinase-resistant form PrP...
Articles
Biochem Soc Trans (2005) 33 (2): 375–379.
Published: 01 April 2005
... The Biochemical Society 2005 abiotic stress abscisic acid (ABA) osmoregulation reactive oxygen species (ROS) upstream sensing upstream signalling Abiotic stress can limit crop productivity and is a key determinant of the natural distribution of plant species. Abiotic stresses, such as low water...
Articles
Biochem Soc Trans (2004) 32 (6): 1018–1020.
Published: 26 October 2004
... 2004 hydrogen peroxide phosphatase protein tyrosine phosphatase (PTP) reactive oxygen species (ROS) redox signalling superoxide Regulated reversible phosphorylation of proteins and other cellular molecules plays a ubiquitous role in the control of cellular behaviour. Several different...
Articles
Biochem Soc Trans (2004) 32 (6): 1070–1071.
Published: 26 October 2004
... Society 2004 elimination of mitochondria fission fusion mitochondrial inhibitors reactive oxygen species (ROS) Mitochondria in various cell types form a dynamic reticulum [ 1 ], which was suggested to play the role of a cable-like energy transporting system in the cell [ 2 ]. In agreement...
Articles
Biochem Soc Trans (2003) 31 (6): 1441–1444.
Published: 01 December 2003
... of the Biochemical Society held at the University of Essex, Colchester, 2–4 July 2003 9 July 2003 © 2003 Biochemical Society 2003 apoptosis growth factor Mn superoxide dismutase Ras reactive oxygen species (ROS) senescence Abbreviations used: AP-1, activator protein-1; DPI...