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Keywords: rapalogue
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Biochem Soc Trans (2011) 39 (2): 451–455.
Published: 22 March 2011
... in cancer patients. 1 email echeverria@sanofi-aventis.com 25 10 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 cancer mammalian target of rapamycin inhibitor (mTOR inhibitor) phosphoinositide 3-kinase (PI3K) rapalogue targeted therapy Compounds...
Biochem Soc Trans (2011) 39 (2): 492–494.
Published: 22 March 2011
...Didier Roulin; Nicolas Demartines; Olivier Dormond Targeting mTOR (mammalian target of rapamycin) is an effective approach in the treatment of advanced RCC (renal cell carcinoma). Rapamycin-like drugs (rapalogues) have shown clinical activities and have been approved for the treatment of RCC...