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Keywords: proteostasis
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Biochem Soc Trans (2022) 50 (2): 759–771.
Published: 21 March 2022
...Sarah Rolli; Emily Mitchell Sontag Properly folded, functional proteins are essential for cell health. Cells sustain protein homeostasis, or proteostasis, via protein quality control (PQC) mechanisms. It is currently hypothesized that a breakdown in proteostasis during ageing leads...
Biochem Soc Trans (2021) 49 (4): 1589–1599.
Published: 09 July 2021
... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gene regulation growth proteostasis ribosome biogenesis Saccharomyces cerevisiae yeast stress response Ribosome biogenesis is probably the most energy-intensive anabolic processes carried out...
Biochem Soc Trans (2020) 48 (1): 199–205.
Published: 17 February 2020
... might regulate ER proteostasis and the implication thereof to general cell physiology. Correspondence: Hesso Farhan ( hesso.farhan@medisin.uio.no ) 19 12 2019 22 1 2020 27 1 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society...
Biochem Soc Trans (2018) 46 (3): 699–706.
Published: 25 May 2018
... fragments to lysosomal compartments for clearance. It gives essential contribution to the maintenance of cellular homeostasis, proteostasis, lipidostasis and oligosaccharidostasis (i.e. the capacity to produce the proteome, lipidome and oligosaccharidome in appropriate quality and quantity). ER turnover...
Biochem Soc Trans (2014) 42 (2): 457–460.
Published: 20 March 2014
... proteostasis unfolded protein response (UPR) We finally succeeded in identifying the novel ATF4-binding site in the 3′-enhancer region of the EPO gene by ChIP assay and found that, under the imbalanced UPR conditions, ATF4 binds to the novel binding site identified near the HIF-binding site...