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Keywords: proteome
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Biochem Soc Trans (2020) 48 (3): 945–954.
Published: 15 May 2020
... such as native MS, top-down proteomics, and ion mobility MS. Other MS-based structural methods include affinity purification MS, chemical cross-linking, and protein footprinting. These methods have enabled the study of protein–protein and protein–ligand interactions and regions of conformational change...
Biochem Soc Trans (2018) 46 (4): 843–853.
Published: 09 July 2018
... mechanism of action microRNA MSC exosome proteome Mesenchymal stem cells (MSCs) are the most extensively used stem cells in the field of regenerative medicine. From 2006 to 2012, the MSC-based product FDA IND submissions increased by threefold [ 1 ]. A simple search using keywords ‘mesenchymal...
Biochem Soc Trans (2015) 43 (6): 1271–1276.
Published: 27 November 2015
...-coding ribonucleic acid (ncRNA) NGS sequencing of footprints from polysome fractions (Poly-Ribo-Seq) proteome ribosome profiling small open reading frames (smORFs) translation The advent of mass sequencing has provided us with the full sequence of genomes and has given rise to the field...
Biochem Soc Trans (2015) 43 (5): 807–811.
Published: 09 October 2015
... that if we want to obtain a collection of structurally and functionally meaningful TRs from a large scale analysis of proteomes, the TR scoring metrics need to be improved. 1 To whom correspondence should be addressed (email andrey.kajava@crbm.cnrs.fr ) . 14 4 2015 © 2015 Authors...
Biochem Soc Trans (2014) 42 (4): 952–958.
Published: 11 August 2014
...Carmelina Petrungaro; Jan Riemer Eukaryotic cells developed diverse mechanisms to guide proteins to more than one destination within the cell. Recently, the proteome of the IMS (intermembrane space) of mitochondria of yeast cells was identified showing that approximately 20% of all soluble IMS...
Biochem Soc Trans (2014) 42 (2): 495–499.
Published: 20 March 2014
..., there is the common technique of real-time RT (reverse transcription)–PCR and direct quantification of mRNA copy number by the Nanostring™ method. For glyoxalase protein quantification, there is the commonly used Western blotting, and also immunoassay and, in proteome-wide studies, quantitative proteomics...
Biochem Soc Trans (2006) 34 (1): 59–63.
Published: 20 January 2006
...S.G.N. Grant Synapse proteomics has recently resulted in a quantum leap in knowledge of the protein composition of brain synapses and its phosphorylation. We now have the first draft picture of the synapse, comprising ∼1000 proteins. This is not matched by available methods of functional analysis...
Biochem Soc Trans (2003) 31 (6): 1491–1496.
Published: 01 December 2003
.... In contrast to the data on the yeast interactome, the coverage in Pronet is more patchy with almost full information where concentrated studies on particular path- ways have been conducted, but sparse elsewhere. Similar Key words: network, interactome, power law, proteome, scale free, yeast two-hybrid...