... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . peroxisomes protein translocation ubiquitin ligase Most peroxisomal metabolic enzymes reside in the lumen (otherwise known as the matrix), but are synthesized...

... with an undefined 14-3-3 protein to recognize phosphorylated TPs and deliver them to translocation complexes [ 37 ]; however, mutation of the relevant phosphorylation site did not impair chloroplast targeting [ 38 ]. chloroplasts organelle biogenesis plastid protein import protein translocation ubiquitin...

... of protein translocation through the essential and ubiquitous Sec system. Inspired and helped by Steve we may finally be making progress. My seminar described our latest hypothesis for the molecular mechanism of protein translocation, supported by results collected in Bristol and Leeds on the tractable...

..., I briefly review the experimental and numerical studies of tight knots in proteins, with a particular emphasis on the estimates of the size of these knots. Next, I discuss the process of protein translocation through the mitochondrial pores and report the results of molecular dynamics simulations...

...I. Collinson Proteins destined for secretion, membrane insertion or organellar import contain signal sequences that direct them to the membrane. Once there, transport machines receive and translocate them appropriately across or into the membrane. The related SecY and Sec61 protein translocation...

... and to the unravelling of the mechanisms of preprotein translocation. 1 To whom correspondence should be addressed (email Neupert@med.uni-muenchen.de ). 21 6 2005 © 2005 The Biochemical Society 2005 chaperone import motor mitochondria mitochondrial translocase protein translocation TIM23...

... across the bilayer. Recent studies have identified some molecular mechanisms that are involved in maintaining the permeability barrier of the endoplasmic reticulum membrane during co-translational protein translocation and integration. These mechanisms are both simple and direct in concept...

... that tail-anchored proteins translocate their C-termini across the endoplasmic reticulum membrane by a mechanism different from that used for Sec61-dependent post-translational signal-peptide-driven translocation. Here we summarize recent results on the insertion of tail-anchored proteins and discuss...

... 679th Meeting of the Biochemical Society held at the University of Essex, Colchester, 2–4 July 2003 30 April 2003 © 2003 Biochemical Society 2003 aspartic protease cell signalling endoplasmic reticulum protein translocation signal peptide peptidase Abbreviations used...

.... endoplasmic reticulum glycosylphosphatidylinositol-anchor addition (GPI-anchor addition) protein translocation signal sequence stop transfer sequence transmembrane domain Abbreviations used: GPI, glycosylphosphatidylinositol; ER, endoplasmic reticulum. 1 To whom correspondence should...