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Keywords: protein phosphatase 1
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Biochem Soc Trans (2020) 48 (5): 2229–2240.
Published: 14 October 2020
...Sarah Lemaire; Mathieu Bollen Inhibitor-2 (I2) ranks amongst the most ancient regulators of protein phosphatase-1 (PP1). It is a small, intrinsically disordered protein that was originally discovered as a potent inhibitor of PP1. However, later investigations also characterized I2 as an activator...
Biochem Soc Trans (2013) 41 (6): 1761–1765.
Published: 20 November 2013
... activity at the outer kinetochore. This gradient is further refined by the association of PP1 (protein phosphatase 1) to the outer kinetochore, which stabilizes kinetochore–microtubule interactions and silences the spindle checkpoint by dephosphorylating Aurora B kinase targets when chromosome bi...