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Keywords: protein kinase B (PKB)
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Articles
Biochem Soc Trans (2013) 41 (2): 681–686.
Published: 21 March 2013
...) mammalian target of rapamycin complex 1 (mTORC1) protein kinase B (PKB) trafficking The metabolic switch to aerobic glycolysis is initiated by TCR (T-cell receptor) activation and then maintained in certain T-cell subsets by cytokines such as IL-2 (interleukin-2) and is crucial for normal T-cell...
Articles
Biochem Soc Trans (2007) 35 (5): 1013–1017.
Published: 25 October 2007
...@cancer.org.uk ). 1 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 protein kinase B (PKB) protein kinase C (PKC) phosphoinositide-dependent kinase 1 (PDK1) phosphorylation pleckstrin homology domain (PH domain) protein serine/threonine kinase In mammals...
Articles
Biochem Soc Trans (2007) 35 (5): 1302–1305.
Published: 25 October 2007
... kinase B (PKB) protein turnover The machinery of the body, i.e. muscle, tendon, ligament and bone, accounts for the overwhelming amount of protein-bound amino acid in the body, with the collagen in connective tissue alone accounting for approx. 3 kg of body weight. We now have a much better idea...
Articles
Biochem Soc Trans (2007) 35 (2): 199–203.
Published: 20 March 2007
...) phosphorylation protein kinase B (PKB) Recent experimental evidence argues against the model of ‘surplus’ p85 over p110: PI3K catalytic activity positively controls insulin signalling [ 18 – 20 ] and in vitro PI3K lipid kinase activity present in PI3K immunoprecipitates is reduced in insulin...
Articles
Biochem Soc Trans (2007) 35 (2): 231–235.
Published: 20 March 2007
... brian.hemmings@fmi.ch ). 16 12 2006 © 2007 The Biochemical Society 2007 adipocyte differentiation cancer glucose homoeostasis mouse model phosphatase and tensin homologue deleted on chromosome 10 (PTEN) protein kinase B (PKB) The serine/threonine kinase PKB (protein kinase B, also...
Articles
Biochem Soc Trans (2006) 34 (2): 209–212.
Published: 20 March 2006
..., and place specific emphasis on the role of these pathways in insulin-stimulated glucose uptake. 1 To whom correspondence should be addressed (email j.tavare@bristol.ac.uk ). 21 11 2005 © 2006 The Biochemical Society 2006 AS160 glucose homoeostasis GTPase insulin protein kinase...
Articles
Biochem Soc Trans (2004) 32 (5): 781–784.
Published: 26 October 2004
... together with our previous observation that protein kinase B phosphorylation is normal in Vav-deficient B-cells, we suggest that PI3K activation is Vav-independent in response to strong signals delivered by multivalent cross-linking. B-lymphocyte phosphoinositide 3-kinase (PI3K) protein kinase B (PKB...