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Keywords: protein complex
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Biochem Soc Trans (2017) 45 (3): 599–611.
Published: 15 June 2017
...Gábor Maksay; Joseph A. Marsh The assembly of proteins into complexes is fundamental to nearly all biological signalling processes. Symmetry is a dominant feature of the structures of experimentally determined protein complexes, observed in the vast majority of homomers and many heteromers. However...
Biochem Soc Trans (2016) 44 (2): 562–567.
Published: 11 April 2016
... to selectively and therapeutically target GPCRs. 1 To whom correspondence should be addressed ( michelle.halls@monash.edu ). 25 11 2015 © 2016 Authors; published by Portland Press Limited 2016 cAMP compartmentalization G protein G protein-coupled receptor (GPCR) protein complex...
Biochem Soc Trans (2014) 42 (6): 1786–1791.
Published: 17 November 2014
... activities. 1 To whom correspondence should be addressed (email elahpic@research.haifa.ac.il ). 26 8 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 COP9 signalosome (CSN) moonlighting protein pleiotropy promiscuity protein complex proteasome lid...
Biochem Soc Trans (2012) 40 (3): 475–491.
Published: 22 May 2012
.... 1 To whom correspondence should be addressed (email sat@mrc-lmb.cam.ac.uk ). 1 3 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 allostery dynamics oligomerization p53 protein complex quaternary structure Over the last two decades, it has...
Biochem Soc Trans (2010) 38 (4): 879–882.
Published: 26 July 2010
...A.J. Venkatakrishnan; Emmanuel D. Levy; Sarah A. Teichmann Homo-oligomeric protein complexes are functionally vital and highly abundant in living cells. In the present article, we review our current understanding of their geometry and evolution, including aspects of the symmetry of these complexes...
Biochem Soc Trans (2010) 38 (4): 883–887.
Published: 26 July 2010
... characterization of the proteins involved in such multimeric assemblies. Advances in MS have made possible the identification of multisubunit protein complexes isolated from cell lysates with high sensitivity and accuracy, whereas the TAP (tandem affinity purification) methodology efficiently isolates native...