... and functional details of protein–lipid interactions. Most recently, advances in cryo-EM have demonstrated that SMA-extracted membrane proteins are a rich-source of structural data. For example, it has been possible to resolve the details of annular lipids and protein–protein interactions within complexes...

... in bilayers [ 19 ] will translate to alterations in protein–lipid interactions. Confounding any interpretation of MLCL–protein interactions is the problem that the molecular mechanism through which CL optimises protein activity is itself unclear. However, this does mean that a greater understanding...

... to lipid nanodiscs, and released from native-like lipid vesicles all shed new light on the role of lipid interactions. The unique ability of native MS to capture and interrogate protein–protein, protein–ligand, and protein–lipid interactions opens exciting new avenues for the study of peripheral membrane...

... structures. © 2005 The Biochemical Society 2005 hydrophobicity scale membrane protein molecular dynamics protein–lipid interactions transmembrane ER endoplasmic reticulum This work was supported by grants from the National Institute of General Medical Sciences...