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Biochem Soc Trans (2015) 43 (5): 1075–1078.
Published: 09 October 2015
... 4 2015 © 2015 Authors; published by Portland Press Limited 2015 forkhead box P3 (FOXP3) lymphocytes proliferation regulatory T-cells tribbles-1 (TRIB1) Tribbles pseudokinase 1 (TRIB1) is a serine-threonine kinase-like protein with no known catalytic activity which has been...
Ahmed Lawan, Emma Torrance, Sameer Al-Harthi, Muhannad Shweash, Sulaiman Alnasser, Thikryat Neamatallah, Juliane Schroeder, Robin Plevin
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
.... Cadalbert L. McCluskey A.G. Shweash M. Grassia G. Grant A. Boyd M. Currie S. Plevin R. Deletion of the dual specific phosphatase-4 (DUSP-4) gene reveals an essential non-redundant role for MAP kinase phosphatase-2 (MKP-2) in proliferation and cell survival J. Biol. Chem...
Melanie J. Welham, Emmajayne Kingham, Yolanda Sanchez-Ripoll, Benjamin Kumpfmueller, Michael Storm, Heather Bone
Biochem Soc Trans (2011) 39 (2): 674–678.
Published: 22 March 2011
... pluripotency, proliferation and differentiation (i.e. cell fate) need to be understood so that pluripotency can be maintained during expansion, while differentiation to specific lineages can be induced accurately when required. The present review focuses on the potential roles that PI3K (phosphoinositide 3...
Biochem Soc Trans (2011) 39 (2): 466–471.
Published: 22 March 2011
..., proliferation and survival. In the present paper, we review recent evidence highlighting the notion that the TSC1/2 complex simultaneously controls mTOR-dependent and mTOR-independent signals critical for the balancing of cell proliferation and cell death. 1 To whom correspondence should be addressed...
Biochem Soc Trans (2007) 35 (5): 1329–1333.
Published: 25 October 2007
... kinase) kinase] and ERK phosphorylation leading to an increase in cell proliferation, cell survival, transformation, tumorigenicity, invasion and vascular development. Many of these hallmarks of cancer can be reversed by treatment of cells with siRNA (small interfering RNA) to BRAF or by inhibiting MEK...
Biochem Soc Trans (2005) 33 (4): 694–697.
Published: 01 August 2005
... the normal maintenance of this tissue: differentiation, migration, proliferation and apoptosis. Indeed, APC is involved in the regulation of β-catenin and it also is an important regulator of the cytoskeleton. Thus mutations in APC lead to the accumulation of β-catenin, which causes changes...
Biochem Soc Trans (2003) 31 (6): 1220–1225.
Published: 01 December 2003
... differentiation growth factor receptor lysophosphatidic acid p42/p44 mitogen-activated protein kinase proliferation sphingosine 1-phosphate (S1P) Abbreviations used: ASM, airway smooth muscle; GPCR, G-protein-coupled receptor; GRK2, G-protein-coupled receptor kinase 2; IGF-1, insulin-like growth...