... to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind...

... levels shows genetic modulation, can change according to the physiological and pathological status of the animal and can be programmed by neonatal events. Since the tissue response to changes in circulating glucocorticoid levels can be very rapid, changes in ultradian rhythm could allow tissue-specific...