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Keywords: primary cilium
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Biochem Soc Trans (2021) 49 (6): 2831–2839.
Published: 08 November 2021
... system and the kidney, respectively. Many studies highlight the involvement of the primary cilium, a microtubule-based antenna present at the surface of many cell types, in the integration of extracellular stimuli. The cross-talk between the molecular machinery of autophagy and that of the primary cilium...
Biochem Soc Trans (2007) 35 (1): 124–128.
Published: 22 January 2007
... dominant polycystic kidney disease has revealed a link between TRP channel function, mechanosensation and the role of the primary cilium in renal cyst formation. The PKD2 gene encodes TRPP2 (transient receptor potential polycystin 2) that has significant homology to voltage-activated calcium and sodium TRP...