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Keywords: pre-implantation embryo
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Biochem Soc Trans (2013) 41 (3): 711–719.
Published: 23 May 2013
..., including global changes to DNA methylation and histone modifications and, in female human ESCs, to the epigenetic process of X chromosome inactivation. Epigenetic perturbations have also been detected during culture of pre-implantation embryos; limited research undertaken in mouse suggests a direct effect...