... on how changes in N-glycosylation relates to the success of trophoblast infiltration, interactions of immunomodulators, and uterine angiogenesis. We also discuss studies that suggest aberrant N-glycosylation of trophoblasts may contribute to the pathogenesis of pregnancy complications (e.g. pre-eclampsia...

... of the chemokine RANTES/CCL5 Biochem. Soc. Trans. 2011 39 1649 1653 17 Bates D.O. An unexpected tail of VEGF and PlGF in pre-eclampsia Biochem. Soc. Trans. 2011 39 1576 1582 18 Ramma W. Ahmed A. Is inflammation the cause of pre-eclampsia? Biochem Soc. Trans. 2011 39...

...Wenda Ramma; Asif Ahmed It has been proposed that either excessive inflammation or an imbalance in angiogenic factors cause pre-eclampsia. In the present review, the arguments for and against the role of inflammation and/or angiogenic imbalance as the cause of pre-eclampsia are discussed...

... to macromolecules of the VEGF family of proteins and receptors. It has been shown that responses of endothelial cells in intact vessels to plasma from patients with pre-eclampsia is VEGF-dependent. It has recently been shown that this may be specific to the VEGF 165 b isoform, and blocked by addition of recombinant...

...Asif Ahmed; Melissa J. Cudmore Pre-eclampsia, a pregnancy-specific multi-organ syndrome characterized by widespread endothelial damage, is a new risk factor for cardiovascular disease. No therapies exist to prevent or treat this condition, even to achieve a modest improvement in pregnancy length...

... such as gestational diabetes, pre-eclampsia and intra-uterine growth retardation, representing an effect or a cause of disturbances in the feto/placento/maternal unit. 1 To whom correspondence should be addressed (e-mail fusch@mail.uni-greifswald.de ) 27 11 2000 © 2001 Biochemical Society 2001...