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Keywords: polymer physics
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Biochem Soc Trans (2021) 49 (4): 1675–1684.
Published: 20 July 2021
... inside the cell nucleus. Genome architecture is linked to vital functional purposes, yet a full comprehension of the mechanisms behind DNA folding is still far from being accomplished. Theoretical approaches based on polymer physics have been employed to understand the complexity of chromatin...
Biochem Soc Trans (2013) 41 (2): 582–588.
Published: 21 March 2013
... in this field. 1 To whom correspondence should be addressed (email cbrackle@ph.ed.ac.uk ). 10 9 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 Brownian dynamics simulations DNA looping facilitated diffusion polymer physics search on DNA In living...
Biochem Soc Trans (2013) 41 (2): 508–512.
Published: 21 March 2013
...-dimensional architecture is orchestrated. In the present article, we review the application of a model based on classical polymer physics, the strings and binders switch model, to explain the molecular mechanisms of chromatin self-organization. We explore the scenario where chromatin architecture is shaped...
Biochem Soc Trans (2013) 41 (2): 612–615.
Published: 21 March 2013
... observed size of a chromosome territory. Reasonably, then, we should expect to observe ‘unusual’ polymer physics from the study of chromosome behaviour, in particular chromatin fibres inside the nucleus would probably not behave as standard equilibrated polymer chains. While being an intriguing...