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Keywords: polyglutamine diseaseClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 738–742.
Published: 25 October 2006
... hallmarks of other tauopathies and in polyglutamine diseases such as Huntington's disease. UBB +1 is not present in synucleinopathies such as Parkinson's disease. We showed that UBB +1 causes UPS dysfunction, aggregation and apoptotic cell death. UBB +1 is also present in non-neurological cells, hepatocytes...