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Keywords: polycystic kidney disease
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Biochem Soc Trans (2021) 49 (3): 1171–1188.
Published: 22 June 2021
...Taylor Richards; Kavindiya Modarage; Soniya A. Malik; Paraskevi Goggolidou Polycystic Kidney Disease (PKD) refers to a group of disorders, driven by the formation of cysts in renal tubular cells and is currently one of the leading causes of end-stage renal disease. The range of symptoms observed...
Biochem Soc Trans (2016) 44 (6): 1745–1751.
Published: 02 December 2016
... the burden of chronic kidney disease and also affect on its progression. ATMIN cilia polycystic kidney disease Wnt proteins The cilium is an evolutionarily conserved, microtubule-based organelle, the existence of which was discovered >200 years ago. Although it contains similarities...
Biochem Soc Trans (2007) 35 (1): 124–128.
Published: 22 January 2007
... dominant polycystic kidney disease has revealed a link between TRP channel function, mechanosensation and the role of the primary cilium in renal cyst formation. The PKD2 gene encodes TRPP2 (transient receptor potential polycystin 2) that has significant homology to voltage-activated calcium and sodium TRP...