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Keywords: poly-arginine
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H.M. Moulton, S. Fletcher, B.W. Neuman, G. McClorey, D.A. Stein, S. Abes, S.D. Wilton, M.J. Buchmeier, B. Lebleu, P.L. Iversen
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (4): 826–828.
Published: 20 July 2007
... it with a mannosylated serine moiety or replacing it with the R 9 F 2 CPP significantly decreased the efficacy of the resulting PPMO (CPP–PMO conjugate). We attribute the success of this CPP to its stability in serum and its capacity to transport PMO to RNA targets in a manner superior to that of poly-arginine CPPs...
