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Biochem Soc Trans (2021) 49 (6): 2737–2748.
Published: 16 November 2021
... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Cry2 LOV optogenetics phage-display photoreceptors PYP Photoswitchable proteins undergo a structural change upon irradiation. In some cases, the change results in a change of the fluorescent...
Biochem Soc Trans (2018) 46 (6): 1463–1473.
Published: 21 November 2018
...Roly Megaw; Toby W. Hurd Retinitis pigmentosa (RP) is the leading cause of inherited blindness. RP is a genetically heterogeneous disorder, with more than 100 different causal genes identified in patients. Central to disease pathogenesis is the progressive loss of retinal photoreceptors...
David A. Parfitt, Amelia Lane, Conor Ramsden, Katarina Jovanovic, Peter J. Coffey, Alison J. Hardcastle, Michael E. Cheetham
Biochem Soc Trans (2016) 44 (5): 1245–1251.
Published: 19 October 2016
...David A. Parfitt; Amelia Lane; Conor Ramsden; Katarina Jovanovic; Peter J. Coffey; Alison J. Hardcastle; Michael E. Cheetham The photoreceptor cells in the retina have a highly specialised sensory cilium, the outer segment (OS), which is important for detecting light. Mutations in cilia-related...