... acquired resistance mass spectrometry (MS) phosphoprotein signalling network therapeutic resistance Over the last two decades, monotherapies targeting aberrantly activated oncogenic kinases have emerged as frontline options for many human cancers. For these targeted therapeutics and for others...

... phosphorylation. Protein phosphorylation belongs among the most rapid post-translational modifications. To date, only Arabidopsis thaliana and tobacco ( Nicotiana tabacum ) mature pollen have been subjected to phosphoproteomic studies in order to identify the phosphoproteins present. In the present mini-review...

...Raghuvir Viswanatha; Anthony Bretscher; Damien Garbett Microvilli are found on the apical surface of epithelial cells. Recent studies on the microvillar proteins ezrin and EBP50 (ezrin/radixin/moesin-binding phosphoprotein of 50 kDa) have revealed both the dynamics and the regulation of microvillar...