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Keywords: phospholipid
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Articles
Biochem Soc Trans (2020) 48 (3): 837–851.
Published: 29 June 2020
...Manabu Kitamata; Takehiko Inaba; Shiro Suetsugu Lipid compositions of cells differ according to cell types and intracellular organelles. Phospholipids are major cell membrane lipids and have hydrophilic head groups and hydrophobic fatty acid tails. The cellular lipid membrane without any protein...
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Biochem Soc Trans (2020) 48 (3): 1035–1046.
Published: 03 June 2020
...Luis Alberto Luévano-Martínez; Anna L. Duncan Cardiolipin (CL) and its precursor phosphatidylglycerol (PG) are important anionic phospholipids widely distributed throughout all domains of life. They have key roles in several cellular processes by shaping membranes and modulating the activity...
Includes: Supplementary data
Articles
Biochem Soc Trans (2014) 42 (5): 1367–1371.
Published: 18 September 2014
... in terms of ATP hydrolysis, but the trajectory taken by the phospholipid substrate through the enzyme is a matter of current active research. There are currently three different models for this trajectory, all with support by mutation/activity measurements and analogies with known atomic structures...
Articles
Biochem Soc Trans (2014) 42 (1): 206–211.
Published: 23 January 2014
... © The Authors Journal compilation © 2014 Biochemical Society 2014 Candida albicans Cdc42 filamentous growth G-protein phospholipid Saccharomyces cerevisiae A number of fungi can grow by asexual reproduction via budding growth, in which a small bud is formed on a mother cell...
Articles
Biochem Soc Trans (2011) 39 (4): 1000–1005.
Published: 20 July 2011
... is unknown. CETP belongs to a family that may have evolved from an ancestral lipid binding protein; members of this family include BPI (bactericidal/permeability-increasing protein), LBP (lipopolysaccharide-binding protein) and PLTP (phospholipid-transfer protein) [ 54 ]. BPI was the first member...
Articles
Biochem Soc Trans (2011) 39 (3): 833–837.
Published: 20 May 2011
... 2011 acyl-CoA cardiolipin (diphosphatidylglycerol) carnitine palmitoyltransferase phospholipid recombinant carnitine palmitoyltransferase II (recombinant CPT2) The earliest known and best-defined role for carnitine is its requirement for the mitochondrial oxidation of long-chain fatty...
Articles
Biochem Soc Trans (2011) 39 (3): 775–779.
Published: 20 May 2011
... it is difficult to identify the bound molecules. In our studies, heavy-atom-labelled phospholipids and detergents have been used to unequivocally identify these binding sites at the surfaces of test membrane proteins, the reaction centres from Rhodobacter sphaeroides and Blastochloris viridis . The generality...
Articles
Biochem Soc Trans (2011) 39 (3): 761–766.
Published: 20 May 2011
... Journal compilation © 2011 Biochemical Society 2011 Ca 2+ -ATPase hydrophobic matching lipid–protein interaction membrane protein phospholipid potassium channel Most biological membranes contain a complex mixture of lipid molecules differing in their polar regions and in their fatty...
Articles
Biochem Soc Trans (2011) 39 (3): 767–774.
Published: 20 May 2011
...William Dowhan; Mikhail Bogdanov To determine how the lipid environment affects membrane protein structure and function, strains of Escherichia coli were developed in which normal phospholipid composition can be altered or foreign lipids can be introduced. The properties of LacY (lactose permease...
Articles
Biochem Soc Trans (2007) 35 (5): 890–894.
Published: 25 October 2007
... to by TRPC [TRP (transient receptor potential) canonical] channel subunits. Instead of being voltage-gated, these channels are chemically gated – importantly, by key phospholipid factors of vascular development and disease. This brief review focuses on the hypothesis that the transition to a modulated cell...
Articles
Biochem Soc Trans (2007) 35 (1): 101–104.
Published: 22 January 2007
... several factors are known to stimulate the channel, understanding of its endogenous activators and functions is limited. This paper provides a brief and focused review of our latest findings that show that TRPC5 is a sensor of important signalling phospholipids, including lysophosphatidylcholine...
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Articles
Biochem Soc Trans (2005) 33 (5): 1150–1153.
Published: 26 October 2005
...G.M. Carman The yeast Saccharomyces cerevisiae has the ability to cope with a variety of stress conditions (e.g. zinc deficiency) by regulating the expression of enzyme activities including those involved with phospholipid synthesis. Zinc is an essential mineral required for the growth...
Articles
Biochem Soc Trans (2005) 33 (5): 934–937.
Published: 26 October 2005
...S. Yoshikawa Bovine heart cytochrome c oxidase is a large multi-component membrane protein containing several phospholipids. X-ray structures of this enzyme at high resolution, determined recently, show a trigonal planar structure of Cu B site in the O 2 reduction site, which could contribute...
Articles
Biochem Soc Trans (2005) 33 (5): 938–942.
Published: 26 October 2005
... the ‘hairpin’-loop typical for bound phospholipids. Stabilization of the phosphodiester group is accomplished via an ion pair with Lys 272 of cytochrome c 1 (CYT1), and Ser 73 of RIP1 is present as a polar ligand. The 2Fo-Fc electron density map after refinement of the lipid is contoured at 1σ (white...
Articles
Biochem Soc Trans (2005) 33 (5): 1141–1145.
Published: 26 October 2005
... biosynthesis). Mutations to MET30 cause defects in both the MAM as a donor of PtdSer, and the mitochondria as an acceptor of PtdSer in the transport reaction. PtdSer transport to the locus of Psd2p is controlled by specific protein and lipid motifs. The C2 (Ca 2+ and phospholipid-binding sequence) domain...
Articles
Biochem Soc Trans (2003) 31 (6): 1341–1342.
Published: 01 December 2003
...P.J. Thornalley Glycation of proteins, nucleotides and basic phospholipids by glucose, glyoxal, methylglyoxal, 3-deoxyglucosone and other saccharide derivatives is potentially damaging to the proteome and mutagenic. It is now recognized that there is an enzymatic defence against glycation – a group...
Articles
Biochem Soc Trans (2001) 29 (2): 341–345.
Published: 01 May 2001
...) made breast cancer cells more susceptible to lipid peroxidation. Studies have indicated that cancer cells may become enriched in CLA during growth in culture. This may make intracellular lipids more susceptible to ordinary Key words: cytotoxicity, lipid peroxidation, phospholipid. Abbreviations used...
Articles
Biochem Soc Trans (2000) 28 (6): 894–897.
Published: 01 December 2000
..., a classical interrelation was observed between thermotropic behaviour and the fatty acid unsaturation of lipids. 1 To whom correspondence should be addressed (e-mail sanina@bio.dvgu.ru ) 20 6 2000 © 2000 Biochemical Society 2000 glycolipid phase transition phospholipid...
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Articles
Biochem Soc Trans (2000) 28 (6): 887–890.
Published: 01 December 2000
...S. N. Goncharova; N. M. Sanina; E. Y. Kostetsky By using the combined approaches of microcalorimetric analysis and polarizing microscopy, the crystal-liquid crystal-isotropic melt phase transition of major phospholipids (phosphatidylcholine and phosphatidylethanolamine) and glycolipids...
Articles
Biochem Soc Trans (2000) 28 (6): 729–732.
Published: 01 December 2000
...H. Härtel; C. Benning To explore the role of digalactosyldiacylglycerol (DGDG) in plants the dgd1 mutant of Arabidopsis thaliana was grown in the presence and absence of inorganic phosphate. Phosphate deficiency in the dgd1 mutant causes a strong decrease in all phospholipids accompanied...