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Keywords: phospholamban
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Articles

Improving cardiac Ca 2+ transport into the sarcoplasmic reticulum in heart failure: lessons from the ubiquitous SERCA2b Ca 2+ pump

Peter Vangheluwe, Frank Wuytack
Journal: Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (3): 781–787.
DOI: https://doi.org/10.1042/BST0390781
Published: 20 May 2011
... the existence of a novel and highly conserved site on the SERCA2 pump mediating Ca 2+ affinity regulation by the unique C-terminus of SERCA2b (2b-tail). It differs from the earlier-described target site of the affinity regulator phospholamban. Targeting this novel site may provide a new approach to improve...
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Articles

Spectroscopic studies of phospholamban variants in phospholipid bilayers

J.C. Clayton, E. Hughes, D.A. Middleton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 913–915.
DOI: https://doi.org/10.1042/BST0330913
Published: 26 October 2005
...J.C. Clayton; E. Hughes; D.A. Middleton Phospholamban (PLB) is a 52 amino acid transmembrane protein found in the sarcoplasmic reticulum of cardiac myocytes, where it regulates the transport of calcium ions by SERCA (sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase). This work has shown...
View article titled, Spectroscopic studies of <span class="search-highlight">phospholamban</span> variants in phospholipid bilayers
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