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Keywords: phosphodiesterase
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Biochem Soc Trans (2014) 42 (2): 257–264.
Published: 20 March 2014
.... Consistent with this, a cAMP-responsive signalling complex that includes Epac1 and PDE4D3 has been identified in cardiac myocytes [ 28 ]. cAMP cardiac disease exchange protein directly activated by cAMP (Epac) G-protein-coupled receptor (GPCR) heart failure phosphodiesterase cAMP...
Biochem Soc Trans (2012) 40 (1): 11–14.
Published: 19 January 2012
... by modulating the activity of PDEs (phosphodiesterases), the enzymes that degrade cyclic nucleotides. This biochemical cross-talk provides the means for drugs that increase cGMP to concomitantly affect cAMP signals. Recent studies using FRET (fluorescence resonance energy transfer) reporters and real-time...
Biochem Soc Trans (2003) 31 (5): 912–915.
Published: 01 October 2003
... April 2003 © 2003 Biochemical Society 2003 adenylate cyclase calmodulin calcium cAMP-dependent protein kinase caveolae phosphodiesterase Abbreviations used: AC1, AC2, AC3, etc., adenylate cyclase types 1, 2, 3, etc; CCE, capacitative Ca 2+ entry; [Ca 2+ ] i , intracellular...