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Keywords: phosphatidylinositol 3,4,5-trisphosphate
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Biochem Soc Trans (2009) 37 (5): 1110–1114.
Published: 21 September 2009
... 3,4,5-trisphosphate phosphatidylinositol 4,5-bisphosphate Bipolar mood disorder is a chronic psychiatric disorder characterized by recurrent episodes of mania and depression. It has a high lifetime prevalence (>1%) and presents a major socioeconomic burden. Although primarily triggered...
Biochem Soc Trans (2007) 35 (2): 211–214.
Published: 20 March 2007
... acid phosphoinositide 3-kinase (PI3K) phosphatidylinositol 3,4,5-trisphosphate A growing list of stimuli has been found to be able to activate class II PI3Ks including (i) chemokines, such as MCP-1 (monocyte chemotactic protein-1) [ 35 ], (ii) cytokines, such as leptin and TNFα (tumour...
Biochem Soc Trans (2007) 35 (2): 257–259.
Published: 20 March 2007
... homologue deleted on chromosome 10 (PTEN) phosphatidylinositol 3,4,5-trisphosphate phosphoinositide 3-kinase (PI3K) vanadate The key event in glucose signalling is the activation of GS (glycogen synthase) and increased glucose uptake, causing the conversion of blood glucose into muscle glycogen...
Biochem Soc Trans (2007) 35 (2): 215–218.
Published: 20 March 2007
...T. Sasaki; J. Sasaki; K. Watanabe; A. Suzuki PI3Ks (phosphoinositide 3-kinases) regulate many critical cellular responses by producing PI(3,4,5) P 3 (phosphatidylinositol 3,4,5-trisphosphate). To facilitate the spatio-temporal characterization of PI(3,4,5) P 3 in living primary cells, we generated...