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Keywords: phosphatase and tensin homologue deleted on chromosome 10 (PTEN)
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Articles
Biochem Soc Trans (2014) 42 (5): 1418–1424.
Published: 18 September 2014
... 10.1038/nrm2934 20606693 four-point-one ezrin radixin moesin (FERM) lipid bilayer molecular dynamics simulation phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphatidylinositol phosphate (PIP) pleckstrin homology (PH) In the context of membrane biology, MD...
Articles
Biochem Soc Trans (2014) 42 (5): 1343–1348.
Published: 18 September 2014
... inhibitors were complemented by the discovery of specific phosphatase and tensin homologue deleted on chromosome 10 (PTEN) inhibitors [ 17 ] that have been used to elucidate the more intricate relationship between 3-phosphorylated inositol lipids and disease development [ 18 ]. In particular, vanadate-based...
Articles
Biochem Soc Trans (2007) 35 (2): 257–259.
Published: 20 March 2007
... homologue deleted on chromosome 10 (PTEN) phosphatidylinositol 3,4,5-trisphosphate phosphoinositide 3-kinase (PI3K) vanadate The key event in glucose signalling is the activation of GS (glycogen synthase) and increased glucose uptake, causing the conversion of blood glucose into muscle glycogen...
Articles
Biochem Soc Trans (2007) 35 (2): 188–192.
Published: 20 March 2007
... to regulate independently the relative levels of PtdIns(3,4,5) P 3 and PtdIns(3,4) P 2 . 1 To whom correspondence should be addressed (email c.p.downes@dundee.ac.uk ). 20 10 2006 © 2007 The Biochemical Society 2007 lipid signal phosphatase and tensin homologue deleted on chromosome...
Articles
Biochem Soc Trans (2007) 35 (2): 172–176.
Published: 20 March 2007
... (email suzuki@med.akita-u.ac.jp ). 28 11 2006 © 2007 The Biochemical Society 2007 cardiovasculogenesis endothelial cell p85α phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphoinositide-3-kinase (PI3K) tumour angiogenesis PTEN (phosphatase...
Articles
Biochem Soc Trans (2007) 35 (2): 231–235.
Published: 20 March 2007
... brian.hemmings@fmi.ch ). 16 12 2006 © 2007 The Biochemical Society 2007 adipocyte differentiation cancer glucose homoeostasis mouse model phosphatase and tensin homologue deleted on chromosome 10 (PTEN) protein kinase B (PKB) The serine/threonine kinase PKB (protein kinase B, also...
Articles
Biochem Soc Trans (2005) 33 (6): 1507–1508.
Published: 26 October 2005
... and tensin homologue deleted on chromosome 10 (PTEN) Little is currently known regarding the mechanism of action of mammalian PTEN in the regulation of cell migration. Data using PTEN mutants lacking the C-terminal PDZ-binding site indicates that binding through a (currently unidentified) PDZ...