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Keywords: phagocytosis
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Articles
Biochem Soc Trans (2023) 51 (3): 1279–1287.
Published: 14 June 2023
...Ojal Saharan; Siddhesh S. Kamat Phagocytosis is an evolutionarily conserved important immunological process in higher organisms, and acts as the first line of defense against invading pathogenic microbial infections. Additionally, this dynamic innate immune response is also critical for clearing...
Articles
Biochem Soc Trans (2022) 50 (5): 1281–1291.
Published: 25 October 2022
...Daan Vorselen Phagocytosis triggered by the phospholipid phosphatidylserine (PS) is key for the removal of apoptotic cells in development, tissue homeostasis and infection. Modulation of PS-mediated phagocytosis is an attractive target for therapeutic intervention in the context of atherosclerosis...
Articles
Biochem Soc Trans (2021) 49 (2): 793–804.
Published: 12 April 2021
... ], the pro-inflammatory consequence of necrosis likely outcompetes the benefit of rapid phagocytic recruitment. Moreover, once recruited to the site of necrosis, phagocytosis and sensing of necrotic debris can further exacerbate inflammation whereby phagocytes release pro-inflammatory cytokines such as IL-8...
Articles
Biochem Soc Trans (2019) 47 (2): 509–516.
Published: 05 April 2019
.... Extracell. Vesicles 3 , 1 – 14 10.3402/jev.v3.24641 26 Feng , D. , Zhao , W.-L. , Ye , Y.-Y. , Bai , X.-C. , Liu , R.-Q. , Chang , L.-F. et al. ( 2010 ) Cellular internalization of exosomes occurs through phagocytosis . Traffic 11 , 675 – 687 10.1111/j.1600...
Articles
Biochem Soc Trans (2015) 43 (5): 920–923.
Published: 09 October 2015
...) amyloid-β peptide microglia phagocytosis ABCA7 is a member of the ‘A’ subfamily of ATP-binding cassette transporters that were initially characterized by their capacity to transport lipids and other lipophilic molecules across membranes [ 9 ]. Similar to ABCA1 (the closest ABCA7 homologue...
Articles
Biochem Soc Trans (2013) 41 (2): 475–490.
Published: 21 March 2013
...Leanne M. Smith; Robin C. May Phagocytosis and phagosome maturation are crucial processes in biology. Phagocytosis and the subsequent digestion of phagocytosed particles occur across a huge diversity of eukaryotes and can be achieved by many different cells within one organism. In parallel, diverse...
Articles
Biochem Soc Trans (2010) 38 (6): 1417–1419.
Published: 24 November 2010
... ). 23 9 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 endocytosis endosome lysosome pathogen phagocytosis phagolysosome How a pathogen manipulates the host is an area of intense research, but identifying the targets of the pathogen proteins can...
Articles
Biochem Soc Trans (2010) 38 (6): 1420–1423.
Published: 24 November 2010
... correspondence should be addressed (email psaftig@biochem.uni-kiel.de ). 26 8 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 autophagy cholesterol homoeostasis lysosome lysosome membrane protein phagocytosis trafficking The lysosomal membrane, a 7–10-nm...
Articles
Biochem Soc Trans (2007) 35 (4): 704–706.
Published: 20 July 2007
..., degradation of collagen occurs primarily through a phagocytic pathway. While various steps in this pathway have been characterized, the enzyme required to fragment collagen fibrils for phagocytosis has not been identified. Laser confocal microscopy, transmission electron microscopy and biochemical assays were...
Articles
Biochem Soc Trans (2007) 35 (2): 261–262.
Published: 20 March 2007
... Kirkham P. Biochem. Soc. Trans. 2007 35 284 287 11 Rossi A.G. Hallett J.M. Sawatzky D.A. Teixeira M.M. Haslett C. Biochem. Soc. Trans. 2007 35 288 291 inflammation inhibitor of nuclear factor κB (IκB) nuclear factor κB (NF-κB) phagocytosis post...
Articles
Biochem Soc Trans (2004) 32 (3): 507–510.
Published: 01 June 2004
... phagocytosis Abbreviations used: ANXA1, annexin 1; GC, glucocorticoid; PLA 2 , phospholipase A 2 ; TNFα, tumour necrosis factor α. Apoptosis in Myeloid Cells 507 Annexin 1 and neutrophil apoptosis M. Perretti*1 and E. Solito *The William Harvey Research Institute, Queen Mary University of London...
Articles
Biochem Soc Trans (2003) 31 (4): 753–757.
Published: 01 August 2003
... through activation of the complement system via MBL-associated serine proteases (MASPs). This can cause the lysis of Gram-negative bacteria and also opsonize a wide spectrum of potential pathogens for phagocytosis. MBL may also influence phagocytosis in the absence of complement activation through...
Articles
Biochem Soc Trans (2003) 31 (2): 449–451.
Published: 01 April 2003
..., were over 65 years old (mean age 82.5 years) and had sustained a fractured neck of femur. We obtained neutrophils and examined the process of microbial engulfment by phagocytosis and the bactericidal mechanism of superoxide production. In the 5-week period after trauma, almost half of the elderly...
Articles
Biochem Soc Trans (2002) 30 (6): 1010–1014.
Published: 01 November 2002
... for phagocytosis enhancement (C1qRp), complement receptor (CR) 1, calreticulin (CRT), binding protein for the globular head of C1q (gC1qbp)] have been described, and the aim of this review is to shed light on their structure-function relationships. One cell-surface molecule, C1qRp, has emerged as a defence...