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Keywords: pertussis toxin
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Biochem Soc Trans (2007) 35 (5): 1035–1037.
Published: 25 October 2007
... the hypothesis that the β 3a -AR interacts with caveolin. Disruption of caveolae in CHO (Chinese-hamster ovary)-K1 cells expressing wild-type β 3a -ARs with filipin III, or mutation of a putative caveolin-binding site in the β 3a -AR, causes cAMP accumulation to become PTX (pertussis toxin)-sensitive. Likewise...