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Keywords: peroxynitrite
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Articles
Biochem Soc Trans (2011) 39 (5): 1279–1287.
Published: 21 September 2011
... signalling activity via interaction with smooth muscle cell guanylate cyclase [ 16 ]. Rapid reaction of NO • with O 2 •− yields the powerful oxidant peroxynitrite (ONOO − /ONOOH, p K a 6.8; reaction 7 [ 17 ]). The neutral (ONOOH) form of this oxidant is highly reactive and undergoes two-electron...
Articles
Biochem Soc Trans (2007) 35 (5): 1119–1121.
Published: 25 October 2007
...-amyloid, prion protein, ATP or arachidonate) causes microglial proliferation and inflammatory activation; thus PHOX is a key regulator of inflammation. Activation of PHOX alone causes no death, but when combined with expressed iNOS results in extensive neuronal death via peroxynitrite production. 1...
Articles
Biochem Soc Trans (2006) 34 (5): 953–956.
Published: 25 October 2006
... The Biochemical Society 2006 cell death mitochondrion peroxynitrite reactive nitrogen species reactive oxygen species NO can react directly with O 2 to produce NO 2 , which will react with a further NO to give N 2 O 3 . This reaction is slow in solution at in vivo levels of NO and O 2...
Articles
Biochem Soc Trans (2006) 34 (5): 965–970.
Published: 25 October 2006
... of pharmacological and genetic approaches. In this mini review, we will evaluate recent advances made towards understanding the roles of reactive oxygen species in inflammation, focusing in particular on superoxide and peroxynitrite. Given the limited space to cover this broad topic, here we will refer the reader...
Articles
Biochem Soc Trans (2003) 31 (6): 1302–1304.
Published: 01 December 2003
... of Essex, Colchester, 2–4 July 2003 1 July 2003 © 2003 Biochemical Society 2003 hydroxyl radical oxidative stress peptoid peroxynitrite reactive oxygen and nitrogen species (RONS) redox-active metal ion Abbreviations used: ET 1 , EDTA mono(methyl tyrosinate); ET 2...
Articles
Biochem Soc Trans (2003) 31 (6): 1133–1136.
Published: 01 December 2003
... studies this inhibition appears to be of M-CPT I rather than L-CPT I; (iii) nitration of M-CPT I occurs, probably by peroxynitrite, and this may be responsible for the decrease in CPT I activity; (iv) myocardial CPT I activity is also inhibited in another model of systemic inflammatory response, namely...
Articles
Biochem Soc Trans (1997) 25 (3): 405S.
Published: 01 August 1997
...Victoria C. Stewart; John M. Land; John B. Clark; Simon J. R. Heales © 1997 Biochemical Society 1997 IFN, interferon LPS, lipopolysaccharide MS, multiple sclerosis L-NAME, N-nitro-L-arginine methyl ester NO, nitric oxide NOS, nitric oxide synthase ONOO peroxynitrite 661st...