...Alison Baker; Thomas Lanyon Hogg; Stuart L. Warriner The import of proteins into peroxisomes possesses many unusual features such as the ability to import folded proteins, and a surprising diversity of targeting signals with differing affinities that can be recognized by the same receptor...

...Frederica L. Theodoulou; David J. Carrier; Theresia A. Schaedler; Stephen A. Baldwin; Alison Baker Import of β-oxidation substrates into peroxisomes is mediated by ATP binding cassette (ABC) transporters belonging to subfamily D. In order to enter the β-oxidation pathway, fatty acids are activated...

...Katarzyna Zientara-Rytter; Suresh Subramani Peroxisomes are essential organelles required for proper cell function in all eukaryotic organisms. They participate in a wide range of cellular processes including the metabolism of lipids and generation, as well as detoxification, of hydrogen peroxide...

...Alison Baker; David J. Carrier; Theresia Schaedler; Hans R. Waterham; Carlo W. van Roermund; Frederica L. Theodoulou Peroxisomes are arguably the most biochemically versatile of all eukaryotic organelles. Their metabolic functions vary between different organisms, between different tissue types...

...% during seedling development. Levels of acetyl-CoA were higher in acn1 compared with wild-type, which is counterintuitive to the activity of ACN1 as a peroxisomal acetyl-CoA synthetase. We hypothesize that ACN1 recycles free acetate to acetyl-CoA within peroxisomes in order that carbon remains fed...

... of lipid droplets Curr. Opin. Cell Biol. 2008 20 378 385 9 Binns D. Januszewski T. Chen Y. Hill J. Markin V.S. Zhao Y. Gilpin C. Chapman K.D. Anderson R.G. Goodman J.M. An intimate collaboration between peroxisomes and lipid bodies J. Cell Biol. 2006...

...M. Casteels; M. Sniekers; P. Fraccascia; G.P. Mannaerts; P.P. Van Veldhoven 2-Hydroxyphytanoyl-CoA lyase (abbreviated as 2-HPCL), renamed to 2-hydroxyacyl-CoA lyase (abbreviated as HACL1), is the first peroxisomal enzyme in mammals that has been found to be dependent on TPP (thiamin pyrophosphate...

...R.J.A. Wanders; J.C. Komen In the present paper, we describe the current state of knowledge regarding the enzymology of the phytanic acid α-oxidation pathway. The product of phytanic acid α-oxidation, i.e. pristanic acid, undergoes three cycles of β-oxidation in peroxisomes after which the products...

...A.S. Wierzbicki Peroxisomes are involved in the synthesis and degradation of complex fatty acids. They contain enzymes involved in the α-, β- and ω-oxidation pathways for fatty acids. Investigation of these pathways and the diseases associated with mutations in enzymes involved in the degradation...

... of oil yield and organelle biogenesis and the possible role of acyl-CoAs in regulating these processes. 1 To whom correspondence should be addressed (e-mail iagl@york.ac.uk ) 18 7 2002 © 2002 Biochemical Society 2002 Arabidopsis oilseed β-oxidation peroxisome ACBP...

...N. Latruffe; M. Cherkaoui Malki; V. Nicolas-Frances; B. Jannin; M.-C. Clemencet; F. Hansmannel; P. Passilly-Degrace; J.-P. Berlot The enzymes required for the β-oxidation of fatty acyl-CoA are present in peroxisomes and mitochondria. Administration of hypolipidaemic compounds such as clofibrate...

...G. Tilton; J. Shockey; J. Browse We have identified two families of acyl-CoA thioesterase (ACHs) in Arabidopsis thaliana. One family, consisting of AtACH1 and AtACH2, appears to be peroxisomal, as they have type-1 peroxisomal targeting sequences. The other family, consisting of AtACH4 and AtACH5...

... mobilization. 1 To whom correspondence should be addressed (e-mail iag@cnap.york.ac.uk ) 26 6 2000 © 2000 Biochemical Society 2000 lipid breakdown β-oxidation peroxisome 2,4-DB, 2,4-dichlorophenoxybutyric acid 2,4-D, 2,4-dichlorophenoxyacetic acid TCA, tricarboxylic acid...

...P.J. Eastmond; I. A. Graham In germinating oilseeds peroxisomal fatty acid β-oxidation is responsible for the mobilization of storage lipids. This pathway also occurs in other tissues where it has a variety of additional physiological functions. The central enzymatic steps of peroxisomal β...