... species revealed that gene loss (i.e. of plant degrading enzymes and virulence inhibitors) is more important than gene gain in the evolution of pathogenesis [ 35 ]. Furthermore, it has been proposed that horizontal gene transfer of virulence genes has shaped the adaptability of Verticillium dahliae...

... by the cellular phosphatase, calcineurin. This review provides the current state-of-the-art knowledge about the molecular controls of cell fusion-dependent pathogenesis caused by VZV. Correspondence: Stefan L. Oliver ( sloliver@stanford.edu ) 27 9 2020 30 10 2020 3 11 2020 © 2020...

... to elucidate pathogenesis mechanisms of Bp , little is known about how a harmless soil bacterium adapts to different environmental conditions, in particular, the shift to a human host to become a highly virulent pathogen. The bacterium has a large genome encoding an armory of factors that assist the pathogen...

... regulator of PCD in B. cinerea and that proper regulation of the host-induced PCD is essential for pathogenesis in this and other similar fungal pathogens. Figure 1 Apoptotic markers in B. cinerea B05.10 in aged cultures Fungi were grown for 120 h, and samples of mycelium were stained...

... metabolites in various cell types has shed light on mechanisms of disease pathogenesis and may pave the way for future development of new therapies for these LSDs. 1 To whom correspondence should be addressed (email Alessandra.dazzo@stjude.org ). 10 5 2010 © The Authors Journal...

.... Important discoveries linking the metabolism of M. tuberculosis and pathogenesis has renewed interest in this area of research. Previous experimental studies were limited to the analysis of individual genes or enzymes, whereas recent advances in computational systems biology and high-throughput experimental...

... established and are key to our understanding of the pathogenic mechanisms in COPD and may be important for the development of new therapies. There is a relationship between chronic inflammatory diseases and aging, and the processes involved in aging may provide a novel mechanism in the pathogenesis of COPD...

... the role of Tsg101 in cancer pathogenesis. cancer endosomal sorting complex required for transport (ESCRT) endosome multivesicular body (MVB) neurodegeneration pathogenesis The endocytic down-regulation of numerous signalling receptors such as the EGFR (epidermal growth factor receptor...

... of these enzymes and their potential as therapeutic targets. 1 To whom correspondence should be addressed (email eckman@mayo.edu ). 28 7 2005 © 2005 The Biochemical Society 2005 Aβ catabolism Alzheimer's disease endothelin-converting enzyme neprilysin pathogenesis therapeutic...

... July 2002 Copyright 2003 Biochemical Society 2003 pathogenesis pathogen evolution type III system Abbreviations used: Hms, haemin storage. 104 Biochemical Society Transactions (2003) Volume 31, part 1 Yersinia pestis and plague R.W. Titball*1, J. Hill*, D.G. Lawton and K.A...