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Keywords: pathogenesis
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Articles
Biochem Soc Trans (2022) 50 (3): 1259–1268.
Published: 17 June 2022
... infection mycology pathogenesis Fungal pathogens (i.e. fungal organisms able to cause disease in a given host) are of high relevance for human health, affecting annually a billion people and causing 1.5 million deaths worldwide [ 1 ]. In addition, they are a threat to food crops [ 2 ] and other...
Articles
Biochem Soc Trans (2020) 48 (6): 2415–2435.
Published: 01 December 2020
... by the cellular phosphatase, calcineurin. This review provides the current state-of-the-art knowledge about the molecular controls of cell fusion-dependent pathogenesis caused by VZV. Correspondence: Stefan L. Oliver ( sloliver@stanford.edu ) 27 9 2020 30 10 2020 3 11 2020 © 2020...
Articles
Biochem Soc Trans (2020) 48 (2): 569–579.
Published: 13 March 2020
... to elucidate pathogenesis mechanisms of Bp , little is known about how a harmless soil bacterium adapts to different environmental conditions, in particular, the shift to a human host to become a highly virulent pathogen. The bacterium has a large genome encoding an armory of factors that assist the pathogen...
Articles
Biochem Soc Trans (2011) 39 (5): 1493–1498.
Published: 21 September 2011
... regulator of PCD in B. cinerea and that proper regulation of the host-induced PCD is essential for pathogenesis in this and other similar fungal pathogens. Figure 1 Apoptotic markers in B. cinerea B05.10 in aged cultures Fungi were grown for 120 h, and samples of mycelium were stained...
Articles
Biochem Soc Trans (2010) 38 (6): 1453–1457.
Published: 24 November 2010
... metabolites in various cell types has shed light on mechanisms of disease pathogenesis and may pave the way for future development of new therapies for these LSDs. 1 To whom correspondence should be addressed (email Alessandra.dazzo@stjude.org ). 10 5 2010 © The Authors Journal...
Articles
Biochem Soc Trans (2010) 38 (5): 1286–1289.
Published: 24 September 2010
.... Important discoveries linking the metabolism of M. tuberculosis and pathogenesis has renewed interest in this area of research. Previous experimental studies were limited to the analysis of individual genes or enzymes, whereas recent advances in computational systems biology and high-throughput experimental...
Articles
Biochem Soc Trans (2009) 37 (4): 819–823.
Published: 22 July 2009
... established and are key to our understanding of the pathogenic mechanisms in COPD and may be important for the development of new therapies. There is a relationship between chronic inflammatory diseases and aging, and the processes involved in aging may provide a novel mechanism in the pathogenesis of COPD...
Articles
Biochem Soc Trans (2009) 37 (1): 167–172.
Published: 20 January 2009
... the focus of several excellent reviews [ 1 – 3 ], but here we focus on the endocytic and non-endocytic functions of the ESCRTs in cellular pathogenesis. Table 1 Summary of the diseases in humans associated with the MVB pathway FTLD-U, frontotemporal lobar dementia with ubiquitin-immunoreactive...
Articles
Biochem Soc Trans (2005) 33 (5): 1101–1105.
Published: 26 October 2005
... [ 20 ] and Type II (non-insulin-dependent) diabetes mellitus [ 21 ]. In APP transgenic mice, diet-induced insulin resistance results in increased amyloid deposition associated with decreased IDE activity and increased Aβ production [ 22 ]. The effect of IDE variants on AD pathogenesis may depend...
Articles
Biochem Soc Trans (2003) 31 (1): 104–107.
Published: 01 February 2003
... July 2002 Copyright 2003 Biochemical Society 2003 pathogenesis pathogen evolution type III system Abbreviations used: Hms, haemin storage. 104 Biochemical Society Transactions (2003) Volume 31, part 1 Yersinia pestis and plague R.W. Titball*1, J. Hill*, D.G. Lawton and K.A...