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Keywords: pancreas
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Biochem Soc Trans (2021) 49 (2): 579–590.
Published: 05 March 2021
... with Portland Press and the Biochemical Society under a transformative agreement with JISC. liver pancreas reprogramming transcription factor transdifferentiation Ectopic expression of master regulatory transcription factors is still critical to our ability to transdifferentiate from liver...
Biochem Soc Trans (2014) 42 (3): 609–616.
Published: 22 May 2014
... 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 liver metaplasia pancreas reprogramming transdifferentiation Figure 1 Proposed mechanism for dexamethasone-dependent transdifferentiation of pancreatic B13 cells into hepatocyte-like cells Dexamethasone (Dex...
Biochem Soc Trans (2008) 36 (3): 286–289.
Published: 21 May 2008
...-cell regeneration diabetes glucose metabolism pancreas transgenic model Pancreatic β-cells constitute approx. 80% of the endocrine pancreas, within the so-called islets of Langerhans. The β-cell mass assumes the production and release of insulin in order to regulate blood glucose...
Biochem Soc Trans (2008) 36 (3): 267–271.
Published: 21 May 2008
... g.rutter@imperial.ac.uk ). 9 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 β-cell diabetes insulin pancreas It has become increasingly clear in the last few years that pancreatic β-cell failure or destruction lies at the heart not only of Type 1...
Biochem Soc Trans (2008) 36 (3): 276–279.
Published: 21 May 2008
...Bertrand Duvillié; Volodymyr Stetsyuk; Gaëlle Filhoulaud; Ghislaine Guillemain; Raphaël Scharfmann Understanding pancreatic development is important for at least three reasons: first, from a cognitive point of view, to understand the development of a complex organ, the pancreas; next, because...
Biochem Soc Trans (2005) 33 (2): 371–374.
Published: 01 April 2005
... will affect the liver and pancreas, two tissues that heavily influence glucose homoeostasis. GKAs should enhance insulin secretion but also act on the liver to begin to normalize HGB in T2D patients. Although there may be concerns about the excessive accumulation of liver glycogen or increased conversion...