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Keywords: pancreas
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Articles
Biochem Soc Trans (2021) 49 (2): 579–590.
Published: 05 March 2021
... to the instructive role of pancreatic master regulators in liver to pancreas transdifferentiation and how the recapitulation of the in vivo environment using cell culture techniques can augment their impact in the generation β-cells. Important to normal development is the hierarchical and temporal context...
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Articles
Biochem Soc Trans (2008) 36 (3): 267–271.
Published: 21 May 2008
... g.rutter@imperial.ac.uk ). 9 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 β-cell diabetes insulin pancreas It has become increasingly clear in the last few years that pancreatic β-cell failure or destruction lies at the heart not only of Type 1...
Articles
Biochem Soc Trans (2008) 36 (3): 276–279.
Published: 21 May 2008
...Bertrand Duvillié; Volodymyr Stetsyuk; Gaëlle Filhoulaud; Ghislaine Guillemain; Raphaël Scharfmann Understanding pancreatic development is important for at least three reasons: first, from a cognitive point of view, to understand the development of a complex organ, the pancreas; next, because...
Articles
Biochem Soc Trans (2008) 36 (3): 286–289.
Published: 21 May 2008
... into their β-cell core, might play crucial roles so far unsuspected, which should be explored in the near future. Pancreatic β-cells constitute approx. 80% of the endocrine pancreas, within the so-called islets of Langerhans. The β-cell mass assumes the production and release of insulin in order...
Articles
Biochem Soc Trans (2005) 33 (2): 371–374.
Published: 01 April 2005
... will affect the liver and pancreas, two tissues that heavily influence glucose homoeostasis. GKAs should enhance insulin secretion but also act on the liver to begin to normalize HGB in T2D patients. Although there may be concerns about the excessive accumulation of liver glycogen or increased conversion...