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Keywords: pH-sensor
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Articles
Biochem Soc Trans (2007) 35 (5): 1092–1099.
Published: 25 October 2007
..., we discuss our recent discovery that endosomal V-ATPase is a pH-sensor regulating the degradative pathway. According to our model, V-ATPase is responsible for: (i) the generation of a pH gradient between vesicular membranes; (ii) sensing of intravesicular pH; and (iii) transmitting this information...
Includes: Supplementary data