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Keywords: optimality principles
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Biochem Soc Trans (2017) 45 (4): 1035–1043.
Published: 28 July 2017
...Jan Ewald; Martin Bartl; Christoph Kaleta Understanding optimality principles shaping the evolution of regulatory networks controlling metabolism is crucial for deriving a holistic picture of how metabolism is integrated into key cellular processes such as growth, adaptation and pathogenicity...
Biochem Soc Trans (2017) 45 (3): 839–844.
Published: 15 June 2017
... to vascular endothelial growth factor (VEGF) using optimality principles based on Murray's laws [ 37 ]. However, the secretion of VEGF is up-regulated by the Wnt signalling pathway and is highly dependent on the average oxygen level in the tissue [ 38 , 39 ]. Although the intra-tissue level of metabolites...