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Keywords: oligonucleotide
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Articles
Biochem Soc Trans (2011) 39 (2): 629–634.
Published: 22 March 2011
...Keith R. Fox; Tom Brown Triple-helical nucleic acids are formed by binding an oligonucleotide within the major groove of duplex DNA. These complexes offer the possibility of designing oligonucleotides which bind to duplex DNA with considerable sequence specificity. However, triple-helix formation...
Articles
Biochem Soc Trans (2009) 37 (1): 88–91.
Published: 20 January 2009
..., U.K.) and Malcolm White (St Andrews, U.K.). HR homologous recombination MMR mismatch repair OMT oligonucleotide-mediated transformation PT phosphorothioate ssDNA single-stranded DNA I thank K. Stengel and J. Rockwood for technical assistance and unpublished...
Articles
Biochem Soc Trans (2007) 35 (4): 775–779.
Published: 20 July 2007
... steric-block ON (oligonucleotide) analogues, such as PNAs (peptide nucleic acids) or PMOs (phosphorodiamidate morpholino oligomers), has consequently been inefficient when ONs are conjugated with standard CPPs such as Tat (transactivator of transcription), R 9 (nona-arginine), K 8 (octalysine...
Articles
Biochem Soc Trans (2007) 35 (4): 767–769.
Published: 20 July 2007
... that include oligonucleotides, peptides and proteins, low-molecular-mass drugs, nanoparticles and liposomes. The biochemical properties of different classes of CPP, including various sequences derived from the HIV-1 Tat (transactivator of transcription) [e.g. Tat-(48–60), GRKKRRQRRRPPQ], and the homeodomain...
Articles
Biochem Soc Trans (2003) 31 (3): 654–658.
Published: 01 June 2003
..., immunostimulation, oligonucleotide, phosphorothioate, TLR9. Abbreviations used: AP-1, activator protein-1; CpG, 2 -deoxyribo(cytidine-phosphate- guanosine); ds, double-stranded; IFN- , interferon- ; IL, interleukin; IL-1R, IL-1 receptor; NF- B, nuclear factor- B; PAMP, pathogen-associated molecular pattern; PBMCs...