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Keywords: oesophageal adenocarcinoma
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Biochem Soc Trans (2010) 38 (2): 331–336.
Published: 22 March 2010
...Kirill Pavlov; Carlo C. Maley Research in Barrett's oesophagus, and neoplastic progression to OAC (oesophageal adenocarcinoma), is hobbled by the lack of good pre-clinical models that capture the evolutionary dynamics of Barrett's cell populations. Current models trade off tractability for realism...
Biochem Soc Trans (2010) 38 (2): 364–369.
Published: 22 March 2010
... of the transcription factors that specify tissue identity during normal embryonic development. Barrett's metaplasia describes the development of a columnar/intestinal phenotype in the squamous oesophageal epithelium and is the major risk factor for oesophageal adenocarcinoma. This particular type of cancer has...