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Keywords: octapeptide repeat
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Biochem Soc Trans (2012) 40 (4): 735–738.
Published: 20 July 2012
... cleavage Creutzfeldt–Jakob disease octapeptide repeat prion processing reactive oxygen species (ROS) ADAM a disintegrin and metalloproteinase CDP chronic demyelinating polyneuropathy CJD Creutzfeldt–Jakob disease OR octapeptide repeat PrP prion protein PrP C...
Biochem Soc Trans (2005) 33 (5): 1123–1125.
Published: 26 October 2005
... [ 12 ]. These protective responses to ROS are not observed in the cells expressing PrPΔoct, which fails to undergo β-cleavage, or in cells expressing wtPrP, where β-cleavage is blocked by the binding of antibody SAF32 to the octapeptide repeats [ 12 ]. The observation that ROS-mediated β-cleavage...