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In CollectionEmbryonic development
Biochem Soc Trans (2020) 48 (2): 581–593.
Published: 22 April 2020
... a short period around fertilization, the nucleoli in oocytes and embryos transform into ribosome-biosynthesis-inactive structures termed nucleolus-like or nucleolus precursor bodies (NPBs). For decades, researchers considered these structures to be passive repositories of nucleolar proteins used...
Biochem Soc Trans (2020) 48 (2): 595–612.
Published: 08 April 2020
... and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cancer gene regulation non-coding RNA nucleolus ribosomopathies Ribosome biogenesis is the essential, complex, and tightly regulated process in which large and small ribosomal subunits are assembled. This process...
Biochem Soc Trans (2016) 44 (4): 1086–1090.
Published: 15 August 2016
... 25735853 4 Orsolic I. Jurada D. Pullen N. Oren M. Eliopoulos A.G. Volarevic S. The relationship between the nucleolus and cancer: current evidence and emerging paradigms Semin. Cancer Biol. 2015 37 36 50 10.1016/j.semcancer.2015.12.004 5 Meek D.W...
Biochem Soc Trans (2014) 42 (4): 1224–1228.
Published: 11 August 2014
...Tina McLeod; Akilu Abdullahi; Min Li; Saverio Brogna The nucleolus is the most prominent morphological feature within the nucleus of eukaryotic cells and is best known for its role in ribosome biogenesis. It forms around highly transcribed ribosomal RNA gene repeats which yield precursor rRNAs...
Biochem Soc Trans (2010) 38 (1): 287–291.
Published: 19 January 2010
... Hutchinson–Gilford progeria syndrome (HGPS) Ki67 nucleolus In normal cells, prelamin A, a precursor protein from which mature lamin A is derived, contains a CaaX (where a is an aliphatic residue) motif at the C-terminal end that signals farnesylation of the cysteine residue by the enzyme...
Biochem Soc Trans (2005) 33 (6): 1441–1443.
Published: 26 October 2005
...J.-L. Prieto; B. McStay The nucleolus is the site of rRNA transcription, pre-rRNA processing and ribosome subunit assembly. The nucleolus assembles around clusters of ribosomal gene repeats during late telophase, persists throughout interphase and then disassembles as cells enter mitosis...
Biochem Soc Trans (2004) 32 (4): 557–560.
Published: 01 August 2004
...S.H. Kim; E.V. Ryabov; J.W.S. Brown; M. Taliansky The nucleolus is a prominent subnuclear domain and is classically regarded as the site of transcription of rRNA, processing of the precursor rRNAs and biogenesis of pre-ribosomal particles. In addition to these traditionally recognized activities...
Biochem Soc Trans (2002) 30 (6): 1140–1145.
Published: 01 November 2002
... genetic disease HIV nucleolus DMPK, dystrophica myotonica-protein kinase MDM2, murine double minute 2 Ribozymes and RNA Catalysis: Focused Meeting Organized by D. M. J. Lilley (Department of Biochemistry, University of Dundee) and F. Eckstein (Max-Planck Institute for Experimental...