... histones importins karyopherins nuclear pore complex nuclear protein transport The compartmentalization of the cell into nucleus and cytoplasm is a major feature of all eukaryotic cells. The nuclear envelope separates DNA in the nucleus from protein synthesis process, which occurs...

..., we focus on a subset of nuclear envelope herniations that likely arise as a consequence of disrupting physiological nuclear membrane remodeling pathways required to maintain nuclear envelope homeostasis. For example, stalling of the interphase nuclear pore complex (NPC) biogenesis pathway...

... of how cilia form and function is essential for deciphering ciliopathies and generating therapeutic treatments. cilium intraflagellar transport (IFT) kinesin microtubule nuclear import nuclear pore complex Although kinesin motors are best known as cargo transporters, some kinesin...

... Biochemical Society 2010 Arabidopsis higher plant nuclear envelope (NE) nuclear pore complex Sad1/UNC-84 (SUN) domain The NE (nuclear envelope) is an important but poorly studied dynamic membrane system in plants. Structurally, it is similar to those of other kingdoms; however, few of its...

...M. Stewart Transport of macromolecules between the nuclear and cytoplasmic compartments through NPCs (nuclear pore complexes) is mediated by soluble transport factors that are commonly members of the importin-β superfamily. In the nuclear protein import cycle, importin-β binds cargo...