... support a role for the family in cytoskeletal actin dynamics. In both fruitfly and mouse, the FliI protein is also essential for early development. Recent studies indicate that supervillin, gelsolin and FliI are involved in intracellular signalling via nuclear hormone receptors including the androgen...

... hormone receptor isoform (TRB), which localize to three regions (amino acids 234-282, 310-353 and 429461) of the hormone-binding domain of the receptor. The mutant receptors are transcriptionally impaired, Key words: dominant-negative inhibition, insulin resistance, nuclear hormone receptor. Abbreviations...

... mechanism to integrate DNA methylation fully into gene control in vertebrates. 1 To whom correspondence should be addressed (e-mail awlme@helix.nih.gov ) 29 2 2000 © 2000 Biochemical Society 2000 histone deacetylase nuclear hormone receptor transcriptional repression HDAC...