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Keywords: nuclear factor erythroid 2-related factor 2 (NRF2)
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Articles
Biochem Soc Trans (2015) 43 (4): 595–601.
Published: 03 August 2015
...Svitlana Kurinna; Sabine Werner The nuclear factor erythroid 2-related factor 2 (NRF2) transcription factor is a key player in the cellular antioxidant response and it also controls various other functions in a cell-type specific manner. Due to these key functions, a tight control of NRF2...
Articles
Biochem Soc Trans (2015) 43 (4): 657–662.
Published: 03 August 2015
... that are likely to provoke toxicity in humans. Mammalian cells can adapt to chemical and oxidative stress via the action of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which up-regulates the expression of numerous cell defence genes and has been shown to protect against a variety...