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Keywords: nuclear factor κB (NF-κB)
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Articles
Biochem Soc Trans (2014) 42 (6): 1665–1670.
Published: 17 November 2014
... signalling function to proteins with redox-sensitive thiols. Glrx can regulate vascular hypertrophy and inflammation by regulating the activity of nuclear factor κB (NF-κB) and actin polymerization. Vascular endothelial growth factor (VEGF)-induced endothelial cell (EC) migration is inhibited by Glrx...
Articles
Biochem Soc Trans (2014) 42 (1): 76–81.
Published: 23 January 2014
...@ncl.ac.uk ). 17 7 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cancer cell cycle cyclin D1 mitosis nuclear factor κB (NF-κB) p53 NF-κB (nuclear factor κB) consists of the homo- and hetero-dimers formed from a family of five transcription factors...
Articles
Biochem Soc Trans (2013) 41 (2): 657–663.
Published: 21 March 2013
... compilation © 2013 Biochemical Society 2013 apoptosis B-cell lymphoma (Bcl) hypoxia nuclear factor κB (NF-κB) Apoptosis or programmed cell death is an active process that occurs in response to either internal cell stresses such as DNA damage or external ‘death signals’ generated by cytokines...
Articles
Biochem Soc Trans (2011) 39 (4): 1086–1091.
Published: 20 July 2011
... The Authors Journal compilation © 2011 Biochemical Society 2011 A20 autoimmunity B-cell inflammatory bowel disease (IBD) nuclear factor κB (NF-κB) tumour necrosis factor α-induced protein 3 (TNFAIP3) The NF-κB (nuclear factor κB) family of transcription factors plays a key role...
Articles
Biochem Soc Trans (2010) 38 (5): 1247–1250.
Published: 24 September 2010
... (email M.Marcello@liverpool.ac.uk or M.White@liverpool.ac.uk ). 8 7 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 gene expression regulation inflammatory response nuclear factor κB (NF-κB) oscillation phosphorylation single-cell imaging The NF...
Articles
Biochem Soc Trans (2010) 38 (1): 50–53.
Published: 19 January 2010
... compilation © 2010 Biochemical Society 2010 antiviral activity nuclear factor κB (NF-κB) p53 resveratrol virus Resveratrol (3,4′,5-trihydroxy- trans -stilbene) is a phenolic compound produced by various members of the family of spermatophytes such as grapes. It belongs to the phytoalexin...
Articles
Biochem Soc Trans (2010) 38 (1): 217–222.
Published: 19 January 2010
.... cyclin D1 nuclear factor κB (NF-κB) RNA processing Smad nuclear interacting protein 1 (SNIP1) transcription The CCND1 gene-encoded cyclin D1 protein is tightly regulated by a variety of signalling pathways at the transcriptional level as well as post-transcriptionally, through modulation...
Articles
Biochem Soc Trans (2008) 36 (4): 603–608.
Published: 22 July 2008
... of Bristol, University Walk, Clifton, Bristol BS8 1TD, U.K. (email n.d.perkins@bristol.ac.uk ). 25 4 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 co-activator co-repressor nuclear factor κB (NF-κB) p65 RelA transactivation NF-κB (nuclear factor κB...
Includes: Supplementary data
Articles
Biochem Soc Trans (2008) 36 (3): 449–452.
Published: 21 May 2008
... Biochemical Society 2008 intracellular signalling interleukin-1-receptor-associated kinase (IRAK) nuclear factor κB (NF-κB) Toll-like receptor tumour-necrosis-factor-receptor-associated factor-6 (TRAF-6) vaccinia virus The question of how the immune system initially detects the presence...
Articles
Biochem Soc Trans (2008) 36 (3): 334–339.
Published: 21 May 2008
...@ekmd.huji.ac.il 3 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis β-cell cytokine islet graft rejection nuclear factor κB (NF-κB) Type 1 diabetes Type 1 and Type 2 are the two main forms of diabetes mellitus. T1DM (Type 1 diabetes mellitus...
Articles
Biochem Soc Trans (2007) 35 (6): 1508–1511.
Published: 23 November 2007
...-1β (IL-1β) nuclear factor κB (NF-κB) 1 Present address: Physiological Chemistry Department, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, U.S.A. Caspase 1 was the first member of an evolutionarily conserved family of cysteine-dependent aspartate-specific proteases...
Articles
Biochem Soc Trans (2007) 35 (6): 1479–1484.
Published: 23 November 2007
... factor κB (NF-κB) pattern-recognition molecule (PRM) Sensing and defeating microbial infections is essential for the survival of metazoan species. All living organisms are constantly exposed to microbes that are, most of the time, neutral or beneficial to the host, but sometimes cause infectious...
Articles
Biochem Soc Trans (2007) 35 (5): 942–945.
Published: 25 October 2007
... Journal compilation © 2007 Biochemical Society 2007 de-ubiquitinating enzyme inhibitory κB kinase (IKK) nuclear factor κB (NF-κB) transcription factor tumour necrosis factor receptor (TNFR) ubiquitination The NF-κB (nuclear factor κB) transcription factors are key regulators of immune...
Articles
Biochem Soc Trans (2007) 35 (4): 811–815.
Published: 20 July 2007
...-penetrating peptide (CPP) inflammation nuclear factor κB (NF-κB) protein transduction domain PTDs (protein transduction domains) or CPPs (cell-penetrating peptides) are small peptides which are able to carry much larger molecules such as oligonucleotides, peptides, full-length proteins, 40 nm iron...
Articles
Biochem Soc Trans (2007) 35 (2): 261–262.
Published: 20 March 2007
... and P. Evans (National Heart and Lung Institute, Imperial College London, U.K.). inflammation inhibitor of nuclear factor κB (IκB) nuclear factor κB (NF-κB) phagocytosis post-translational modification protein degradation The resolution of inflammatory responses is a tightly co-ordinated...
Articles
Biochem Soc Trans (2007) 35 (2): 281–283.
Published: 20 March 2007
... 2007 acetylation chronic obstructive pulmonary disease (COPD) glucocorticoid histone deacetylase (HDAC) nuclear factor κB (NF-κB) post-translational modification PTM (post-translational modification) is the chemical modification of a protein after its translation...
Articles
Biochem Soc Trans (2007) 35 (2): 263–266.
Published: 20 March 2007
... The Biochemical Society 2007 inflammatory response nuclear factor κB (NF-κB) oscillation RelA single-cell imaging The NF-κB signalling pathway has been shown to be active in virtually all cell types and to regulate a number of essential cellular functions. These include inflammation, apoptosis...
Articles
Biochem Soc Trans (2007) 35 (2): 277–280.
Published: 20 March 2007
... The Biochemical Society 2007 apoptosis cell proliferation nuclear factor κB (NF-κB) phosphoinositide 3-kinase (PI3K) Src homology 2 domain-containing inositol phosphatase-1 (SHIP1) T-lymphocyte The PI3K (phosphoinositide 3-kinase) pathway regulates many important cellular functions...
Articles
Biochem Soc Trans (2007) 35 (2): 273–276.
Published: 20 March 2007
... 2007 antiprotease host response inflammatory lung disease monocyte nuclear factor κB (NF-κB) secretory leucoprotease inhibitor (SLPI) Human SLPI (secretory leucoprotease inhibitor) was originally isolated from secretions of patients with COPD (chronic obstructive pulmonary disease...
Articles
Biochem Soc Trans (2007) 35 (2): 267–269.
Published: 20 March 2007
... ligase inhibitor of nuclear factor κB (IκB) inhibitor of nuclear factor κB α kinase complex (IKK complex) NEDD8 nuclear factor κB (NF-κB) β-transducin repeat-containing protein (β-TrCP) In most cases the epithelial cell layer represents the first barrier for microbial pathogens and triggers...
Articles
Biochem Soc Trans (2007) 35 (2): 270–272.
Published: 20 March 2007
... t.lawrence@imperial.ac.uk ). 1 11 2006 © 2007 The Biochemical Society 2007 adaptive immunity chemokine dendritic cell (DC) inflammation inhibitor of nuclear factor κB kinase (IKK) nuclear factor κB (NF-κB) Figure 2 Schematic diagram showing the interaction between acute...
Articles
Biochem Soc Trans (2006) 34 (5): 764–769.
Published: 25 October 2006
... have been identified as de-ubiquitinating enzymes and it is unclear whether the removal of ubiquitin is the only function of the JAMM domain [ 12 ]. de-ubiquitinating enzyme DNA repair ovarian tumour protease intracellular signalling nuclear factor κB (NF-κB) ubiquitin C-terminal...
Articles
Biochem Soc Trans (2006) 34 (6): 1291–1294.
Published: 25 October 2006
... κB (IκB) kinase (IKK) nuclear factor κB (NF-κB) stroke tumour necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) Stroke is a frequent clinical disorder. The WHO (World Health Organization) estimates that worldwide 5–6 million people die from strokes every year. Thrombolysis has...
Articles
Biochem Soc Trans (2004) 32 (6): 1087–1089.
Published: 26 October 2004
... total NF-κB inhibition. 1 To whom correspondence should be addressed (email k.j.campbell@dundee.ac.uk ). 5 7 2004 © 2004 The Biochemical Society 2004 chemotherapy nuclear factor κB (NF-κB) post-translational modification RelA transcription UV light NF-κB...
Articles
Biochem Soc Trans (2004) 32 (3): 456–460.
Published: 01 June 2004
... Cells: Molecular Insights into Disease Processes: a Biochemical Society Focused Meeting held at New Edinburgh Royal Infirmary, Little France, Nr. Edinburgh, 19–20 November 2003 25 November 2003 © 2004 Biochemical Society 2004 apoptosis neutrophil nuclear factor κB (NF-κB...
Articles
Biochem Soc Trans (2004) 32 (1): 113–115.
Published: 01 February 2004
... of activated T-cells (NFAT) nuclear factor κB (NF-κB) phospholipase C-γ2 Abbreviations used: BCR, B-cell antigen receptor; BTK, Bruton's tyrosine kinase; PLC-γ2, phospholipase C-γ2; LSM, lipid second messenger; DAG, diacylglycerol; NFAT, nuclear factor of activated T-cells; NF-κB, nuclear factor...