... in the terminal exon of the β-globin gene are not associated with a reduction in β-mRNA accumulation: a mechanism for the phenotype of dominant β-thalassemia Blood 1994 83 2031 2037 7 Brogna S. Wen J. Nonsense-mediated mRNA decay (NMD) mechanisms Nat. Struct. Mol. Biol. 2009 16 107 113...

... of NMD in cellular growth and development of an organism. 1 To whom correspondence should be addressed (email mip22@cam.ac.uk ). 7 6 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 gene expression nonsense-mediated mRNA decay (NMD) premature...

... Biochemical Society 2009 eukaryotic initiation factor 4E (eIF4E) exon junction complex (EJC) homoeostatic control of genes myogenesis nonsense-mediated mRNA decay (NMD) Staufen1 mRNA decay has long been appreciated to constitute a step that is critical for the proper regulation of gene...

... degradation of functional mRNA. mRNA decay nonsense-mediated mRNA decay (NMD) premature translation termination codon processing body (P-body) translation up-frameshift-1 (UPF1) © The Authors Journal compilation © 2008 Biochemical Society 2008 16 3 2008 1 To whom...

...Jikai Wen; Saverio Brogna Translation and mRNA decay are coupled processes; the link is most obvious in the case of NMD (nonsense-mediated mRNA decay). NMD is a mechanism that drastically reduces the level of mRNA harbouring PTCs (premature translation termination codons). The defining event in NMD...