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Keywords: noncanonical Wnt
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Biochem Soc Trans (2020) 48 (1): 231–243.
Published: 25 February 2020
... architecture of tissues and organs. PCP is considered a noncanonical Wnt pathway due to the involvement of Wnt ligands and Frizzled family receptors in the absence of the beta-catenin driven gene expression observed in the canonical Wnt cascade. At the heart of the PCP mechanism are protein complexes capable...