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Keywords: non-steroidal anti-inflammatory drug (NSAID)
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Articles
Biochem Soc Trans (2007) 35 (2): 322–325.
Published: 20 March 2007
...) arginine cancer prevention colon cancer non-steroidal anti-inflammatory drug (NSAID) polyamine The rationale for interest in the ubiquitous polyamines in intestinal and colon carcinogenesis stems from experimental evidence in human cells and genetically altered mouse models indicating...
Articles
Biochem Soc Trans (2007) 35 (2): 364–368.
Published: 20 March 2007
... patients to developing colorectal cancer by triggering the carcinogenic process at a much earlier age, as the mutation required to mutate APC normally takes many years to accumulate. chemoprevention colorectal cancer cytotoxicity non-steroidal anti-inflammatory drug (NSAID) polyamine...
Articles
Biochem Soc Trans (2007) 35 (2): 353–355.
Published: 20 March 2007
...@ircad.u-strasbg.fr 19 9 2006 © 2007 The Biochemical Society 2007 cancer 2-(difluoromethyl)ornithine (DFMO) non-steroidal anti-inflammatory drug (NSAID) ornithine decarboxylase (ODC) polyamine biosynthesis The involvement of polyamines in growth-related processes attracted...
Articles
Biochem Soc Trans (2005) 33 (4): 667–671.
Published: 01 August 2005
... be addressed (email c.paraskeva@bristol.ac.uk ). 1 4 2005 © 2005 The Biochemical Society 2005 adenoma carcinoma chemoprevention colon cyclo-oxygenase 2 (COX-2) non-steroidal anti-inflammatory drug (NSAID) CRC is a major cause of cancer deaths in the U.K. Epidemiological studies...
Articles
Biochem Soc Trans (2003) 31 (2): 388–392.
Published: 01 April 2003
..., in turn, activates the expression of the spermidine/spermine-N 1 -acetyltransferase (SSAT), the first enzyme in polyamine catabolism. The non-steroidal anti-inflammatory drug (NSAID) sulindac induces the transcription of SSAT via activation of PPARγ. Inactivation of the APC tumour-suppressor gene...