... of the whole human epigenomic network. 27 1 2022 18 2 2022 21 2 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 chromatin DNA methylation epigenetics non-coding RNA RNA polymerase The existence of functional non...

...David Llères; Yui Imaizumi; Robert Feil Different classes of non-coding RNA (ncRNA) influence the organization of chromatin. Imprinted gene domains constitute a paradigm for exploring functional long ncRNAs (lncRNAs). Almost all express an lncRNA in a parent-of-origin dependent manner. The mono...

... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 BMP9 crosstalk non-coding rna osteogenesis therapeutics Oral and maxillofacial surgery often aims for both functional and esthetic outcomes, both of which are mostly dependent on the underlying...

.... While many known regulatory factors are proteins or small nucleolar ribonucleoproteins, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs) are emerging as a novel modulatory layer controlling ribosome production. Here, we summarize work uncovering non-coding RNAs (ncRNAs) as novel regulators...

... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biotechnology CRISPR DNA binding endonucleases genome editing non-coding RNA Horizontal gene transfer plays...

...Arlene M.A. Glasgow; Chiara De Santi; Catherine M. Greene Non-coding RNAs (ncRNAs) are an abundant class of RNAs that include small ncRNAs, long non-coding RNAs (lncRNA) and pseudogenes. The human ncRNA atlas includes thousands of these specialised RNA molecules that are further subcategorised...

...Oliver M. Rogoyski; Jose Ignacio Pueyo; Juan Pablo Couso; Sarah F. Newbury Genomic analysis has found that the transcriptome in both humans and Drosophila melanogaster features large numbers of long non-coding RNA transcripts (lncRNAs). This recently discovered class of RNAs regulates gene...

...-coding RNAs supports tumour progression is poorly understood. Here, we review new lines of evidence linking long and short types of non-coding RNAs to signalling pathways activated in the course of cancer progression by growth factors and by the tumour micro-environment. Resolving the new dimension...

... to investigate three distinct CRISPR–Cas defence pathways. clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated (Cas) non-coding RNA prokaryotic immunity Pyrococcus furiosus virus CRISPR Evolution, Mechanisms and Infection: A Biochemical Society Focused Meeting...

... of these ncRNAs (non-coding RNAs) are functional, and if so, what their function is. In this review, we describe recent discoveries in the field of ncRNAs in the yeast Saccharomyces cerevisiae . Newly identified ncRNAs in this budding yeast, their functions in gene regulation and possible mechanisms of action...

...Gwyn T. Williams; Mirna Mourtada-Maarabouni; Farzin Farzaneh Non-coding RNA GAS5 (growth arrest-specific transcript 5) is a 5′-TOP (5′-terminal oligopyrimidine tract) RNA, whose translation, and consequently also stability, is controlled by the mTOR (mammalian target of rapamycin) pathway. GAS5...

...Jan Stenvang; Morten Lindow; Sakari Kauppinen miRNAs (microRNAs) comprise a class of small endogenous non-coding RNAs that post-transcriptionally repress gene expression by base-pairing with their target mRNAs. Recent evidence has shown that miRNAs play important roles in a wide variety of human...

...P. Keller; N. Vollaard; J. Babraj; D. Ball; D.A. Sewell; J.A. Timmons We predict that RNA level regulation is as diverse and powerful as protein level regulation when considering physiological adaptation. Non-coding RNA molecules, such as miRNAs (microRNAs), have emerged as a powerful mechanism...

... large proportion of the mammalian genome is actively transcribed, while a large number of ncNAT molecules exist, some of which are extremely long and can be found in the nucleus [ 8 ]. How does non-coding RNA regulate cell function? RNA duplex formation leading to RNA editing or degradation has...