... of the University of Queensland in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with CAUL. inflammation macrophages mitochondrial dynamics mitochondrial fission mitochondrial fusion neuroinflammation Macrophages...

... (CC BY) . induced pluripotent stem cells leucine-rich repeat kinase macrophages microglia neuroinflammation Parkinson's disease Parkinson's disease (PD) is a complex, multifactorial neurodegenerative disease. In North America, it affects 1.5% of the population over the age of 65...

.... Correspondence: Elisa Greggio ( elisa.greggio@unipd.it ) or Isabella Russo ( isabella.russo@unipd.it ) 28 10 2016 12 12 2016 19 12 2016 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 LRRK2 microglia neuroinflammation neuron...

... as neurodegenerative and psychiatric conditions. It is therefore a target of interest for molecular strategies aimed at imaging neuroinflammation in vivo . For more than 20 years, positron emission tomography (PET) has allowed the imaging of TSPO density in brain using [ 11 C]-( R )-PK11195, a radiolabelled-specific...

... by Portland Press Limited 2015 blood–brain barrier endothelial interleukin-6 (IL-6) NADPH oxidase neuroinflammation tumour necrosis factor-α (TNF-α) Microvascular endothelial cells lining the cerebrovascular capillary network, in conjunction with non-vascular cells (neurons, microglia...

... exposure to inflammatory factors could predispose to long-term diseases including psychiatric disorders. 6 1 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 cerebral palsy neurodevelopment neuroinflammation oligodendrocyte perinatal brain damage Damage...

... have multiple physiological roles including involvement in learning and memory, neuroinflammation, oxidative stress, neuroprotection and neurogenesis. They have also been implicated in the pathology of, or perhaps protective responses to, neurodegenerative diseases. This is particularly the case...

... complement neurodegeneration neuroimmune mediator neuroinflammation retinal ganglion cell (RGC) synaptic pruning In order to form the precise finely tuned neural circuitry of the mature nervous system, a specific and ordered developmental programme must occur. A characteristic series...

... crucial for this effect. © The Authors Journal compilation © 2007 Biochemical Society 2007 bacterial meningitis brain abscess lipoteichoic acid microglia neurodegeneration neuroinflammation Gram-positive bacterial infections of the CNS (central nervous system) occur either as bacterial...

... neuroinflammation and explain the interconnected relationship between deleterious microglial activation, DA neuron damage and neurodegenerative disease. dopaminergic neuron microglia NADPH oxidase neuroinflammation Parkinson's disease reactive oxygen species Several studies suggest that in order...