... of the University of Queensland in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with CAUL. inflammation macrophages mitochondrial dynamics mitochondrial fission mitochondrial fusion neuroinflammation Macrophages...

..., therefore, has increasing significance as this would provide valuable insights into shared pathological mechanisms underlying both inherited and idiopathic PD pathogenesis. induced pluripotent stem cells leucine-rich repeat kinase macrophages microglia neuroinflammation Parkinson's disease...

.... ( 2014 ) LRRK2 and neuroinflammation: partners in crime in Parkinson's disease? J. Neuroinflammation 11 , 52 doi: 10.1186/1742-2094-11-52 13 Parisiadou , L. , Yu , J. , Sgobio , C. , Xie , C. , Liu , G. , Sun , L. et al. ( 2014 ) LRRK2 regulates synaptogenesis...

... and proliferation in preadipocytes Arterioscler. Thromb. Vasc. Biol. 2009 29 239 245 10.1161/ATVBAHA.108.174219 19057021 blood–brain barrier endothelial interleukin-6 (IL-6) NADPH oxidase neuroinflammation tumour necrosis factor-α (TNF-α) This mini review will examine therefore our...

... as neurodegenerative and psychiatric conditions. It is therefore a target of interest for molecular strategies aimed at imaging neuroinflammation in vivo . For more than 20 years, positron emission tomography (PET) has allowed the imaging of TSPO density in brain using [ 11 C]-( R )-PK11195, a radiolabelled-specific...

... neuroinflammation oligodendrocyte perinatal brain damage Damage to the immature brain around the time of birth presents a serious public health problem across the world. The Global Burden of Disease Study estimated that, in 2010, premature birth was the commonest cause of death under the age of 5 years...

... have multiple physiological roles including involvement in learning and memory, neuroinflammation, oxidative stress, neuroprotection and neurogenesis. They have also been implicated in the pathology of, or perhaps protective responses to, neurodegenerative diseases. This is particularly the case...

... complement neurodegeneration neuroimmune mediator neuroinflammation retinal ganglion cell (RGC) synaptic pruning In order to form the precise finely tuned neural circuitry of the mature nervous system, a specific and ordered developmental programme must occur. A characteristic series...

... neuroinflammation and explain the interconnected relationship between deleterious microglial activation, DA neuron damage and neurodegenerative disease. 1 To whom correspondence should be addressed (email mblock@vcu.edu ). 2 7 2007 © The Authors Journal compilation © 2007 Biochemical Society...

... compilation © 2007 Biochemical Society 2007 bacterial meningitis brain abscess lipoteichoic acid microglia neurodegeneration neuroinflammation Gram-positive bacterial infections of the CNS (central nervous system) occur either as bacterial meningitis or as brain abscess, being localized...