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Keywords: necroptosis
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Biochem Soc Trans (2022) 50 (4): 1197–1205.
Published: 30 August 2022
... kinase (RIPK) 1, RIPK3, Z-DNA-binding protein 1 (ZBP1), and TIR domain-containing adapter-inducing IFN-β (TRIF), which are all major players in necroptosis, a distinct form of regulated cell death. Necroptosis is mostly presumed to be a fail-safe form of cell death, occurring in cells in which apoptosis...
Biochem Soc Trans (2022) 50 (1): 529–539.
Published: 15 February 2022
...Sarah E. Garnish; Joanne M. Hildebrand Programmed cell death has long been characterised as a key player in the development of human disease. Necroptosis is a lytic form of programmed cell death that is universally mediated by the effector protein mixed lineage kinase domain-like (MLKL...
Biochem Soc Trans (2022) 50 (1): 13–20.
Published: 15 February 2022
... can contribute to autoinflammatory and autoimmune diseases or life-threatening conditions like sepsis. These diseases generally display increased levels of cell death, which, downstream of the TNF receptor, can either be caspase-dependent (apoptosis) or caspase-independent (necroptosis). Significant...
Biochem Soc Trans (2021) 49 (2): 793–804.
Published: 12 April 2021
... & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with CAUL. apoptosis cell clearance necroptosis necrosis phagocytosis pyroptosis For over 50 years apoptosis has dominated basic and translational research in the cell death field...